Afoxolaner 2.27% Chewable Tablet (136 Mg)

237 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

237

Total Reports

Deaths Reported

300.0%

Death Rate

Active Ingredients

Afoxolaner 2.27% Chewable Tablet (136 Mg)

Administration Routes

OralUnknown

Species Affected

Dog 235

Unknown 1

Horse 1

Most Affected Breeds

Retriever - Labrador 57

Retriever - Golden 26

Shepherd Dog - German 23

Crossbred Canine/dog 21

Rottweiler 12

Pit Bull 10

Dog (unknown) 8

Unknown 7

Boxer (German Boxer) 6

Collie - Border 4

Most Reported Reactions

Vomiting 56

Skin disorders NOS 37

Pruritus 34

Diarrhoea 25

Lethargy (see also Central nervous system depression in 'Neurological') 24

Lack of efficacy (ectoparasite) - flea 21

Lack of efficacy (ectoparasite) - tick NOS 18

Scratching 16

Erythema (for urticaria see Immune SOC) 16

Restlessness 13

Anorexia 12

Itching 12

Outcome Breakdown

Outcome Unknown

112 (47.5%)

Recovered/Normal

99 (41.9%)

Ongoing

11 (4.7%)

Died

7 (3.0%)

Recovered with Sequela

7 (3.0%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.