Drug profile

The FDA adverse-event record for Fvrcp Vaccine

250 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Fvrcp Vaccine. See the species affected, top reactions, and outcomes below.

250
adverse-event reports
14.4%
death-coded share
Cat
most-reported species
48
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
250
Total Reports
36
Deaths Reported
14.4%
Death Rate

Active Ingredients

Fvrcp Vaccine

Administration Routes

UnknownSubcutaneousParenteralNasalIntramuscularSubconjunctivalOral

Species Affected

Cat 250

Most Affected Breeds

Domestic Shorthair 160
Domestic Longhair 21
Domestic Mediumhair 20
Cat (unknown) 13
Maine Coon 6
Cat (other) 4
Unknown 3
Snowshoe 3
Manx 2
Crossbred Feline/cat 2

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 48
Vomiting 43
Death 27
Emesis 24
Anorexia 22
Behavioural disorder NOS 21
Fever 21
Diarrhoea 21
Ataxia 19
Emesis (multiple) 18
Not eating 16
Weight loss 16

Outcome Breakdown

Recovered/Normal
95 (38.0%)
Outcome Unknown
57 (22.8%)
Ongoing
56 (22.4%)
Died
30 (12.0%)
Euthanized
6 (2.4%)
Recovered with Sequela
6 (2.4%)

Fvrcp Vaccine Adverse Event Insights

250 reports name Fvrcp Vaccine; 36 recorded a death outcome (14.4% of reported events, not a population-level mortality rate). Active ingredient: Fvrcp Vaccine. Administration routes: Unknown, Subcutaneous, Parenteral, Nasal.

By species: Cat (250 reports). By breed: Domestic Shorthair (160), Domestic Longhair (21), Domestic Mediumhair (20).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (48), Vomiting (43), Death (27), Emesis (24). Outcome, 250 coded reports: Recovered/Normal leads at 38.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.