Carprofen

22,429 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

22,429

Total Reports

3,351

Deaths Reported

1490.0%

Death Rate

Active Ingredients

Carprofen

Administration Routes

OralUnknownSubcutaneousParenteralOphthalmicIntravenousIntramuscularTopicalOtherSubconjunctival

Species Affected

Dog 20,348

Unknown 1,809

Cat 192

Human 60

Mouse 6

Rat 4

Other Rodents 2

Monkey 2

Guinea Pig 1

Other 1

Most Affected Breeds

Retriever - Labrador 4,267

Unknown 1,960

Crossbred Canine/dog 1,188

Retriever - Golden 1,091

Shepherd Dog - German 894

Dog (unknown) 796

Boxer (German Boxer) 515

Terrier - Bull - American Pit 484

Chihuahua 422

Beagle 418

Most Reported Reactions

Vomiting 5,415

Anorexia 3,293

Elevated alanine aminotransferase (ALT) 3,152

Lethargy (see also Central nervous system depression in 'Neurological') 2,794

Diarrhoea 2,667

Elevated serum alkaline phosphatase (SAP) 2,370

Death by euthanasia 1,902

Elevated total bilirubin 1,700

Other abnormal test result NOS 1,423

Death 1,341

Elevated liver enzymes 1,332

Weight loss 1,308

Outcome Breakdown

Ongoing

7,399 (40.7%)

Recovered/Normal

4,137 (22.8%)

Outcome Unknown

3,100 (17.1%)

Died

1,734 (9.5%)

Euthanized

1,617 (8.9%)

Recovered with Sequela

179 (1.0%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.