Fipronil & S-Methoprene
112 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
112
Total Reports
17
Deaths Reported
1520.0%
Death Rate
Active Ingredients
Fipronil & S-Methoprene
Administration Routes
TopicalUnknown
Species Affected
Dog 80
Cat 32
Most Affected Breeds
Domestic Shorthair 22
Retriever - Labrador 13
Shepherd Dog - German 6
Terrier - Yorkshire 5
Shih Tzu 5
Shepherd Dog - Australian 4
Domestic Longhair 3
Retriever - Golden 3
Mixed (Cat) 2
Bichon Frise 2
Most Reported Reactions
Lethargy (see also Central nervous system depression in 'Neurological') 25
Vomiting 19
Other abnormal test result NOS 15
Seizure NOS 12
Death by euthanasia 11
Elevated alanine aminotransferase (ALT) 11
Anorexia 10
Elevated serum alkaline phosphatase (SAP) 9
Decreased appetite 8
Abnormal radiograph finding 8
Elevated total bilirubin 8
Diarrhoea 7
Outcome Breakdown
Ongoing
49 (43.4%)
Outcome Unknown
25 (22.1%)
Recovered/Normal
22 (19.5%)
Euthanized
10 (8.8%)
Died
7 (6.2%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.