Cyclosporine

9,651 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

9,651

Total Reports

399

Deaths Reported

410.0%

Death Rate

Active Ingredients

Cyclosporine

Administration Routes

OralUnknownOphthalmicTopicalIntraocularCutaneousOtherAuricular (Otic)RectalTransdermal

Species Affected

Dog 5,312

Unknown 2,371

Cat 1,920

Human 47

Other 1

Most Affected Breeds

Unknown 2,424

Domestic Shorthair 954

Crossbred Canine/dog 491

Retriever - Labrador 369

Shih Tzu 331

Cat (unknown) 274

Dog (unknown) 269

Domestic (unspecified) 229

Shepherd Dog - German 223

Terrier - West Highland White 220

Most Reported Reactions

Vomiting 2,185

Diarrhoea 1,067

Lack of efficacy - NOS 537

UNPALATABLE 505

Anorexia 459

Lethargy (see also Central nervous system depression in 'Neurological') 408

Weight loss 400

Product problem 375

Depression 345

Pruritus 344

Other abnormal test result NOS 325

Difficulty of Use 313

Outcome Breakdown

Outcome Unknown

1,549 (33.0%)

Ongoing

1,398 (29.7%)

Recovered/Normal

1,290 (27.4%)

Euthanized

202 (4.3%)

Died

197 (4.2%)

Recovered with Sequela

65 (1.4%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.