Melarsomine Dihydrochloride

9,461 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

9,461

Total Reports

375

Deaths Reported

400.0%

Death Rate

Active Ingredients

Melarsomine Dihydrochloride

Administration Routes

IntramuscularUnknownSubcutaneousParenteralOralOphthalmicIntravenousTopicalOtherIntradermal

Species Affected

Dog 9,221

Unknown 196

Human 40

Cat 4

Most Affected Breeds

Retriever - Labrador 1,348

Crossbred Canine/dog 1,133

Shepherd Dog - German 577

Dog (unknown) 462

Terrier - Bull - American Pit 434

Beagle 410

Chihuahua 375

Boxer (German Boxer) 300

Pit Bull 285

Unknown 245

Most Reported Reactions

Lack of efficacy (endoparasite) - heartworm 2,244

INEFFECTIVE, HEARTWORM ADULTS 1,087

Vomiting 1,067

Injection site swelling 849

Lethargy (see also Central nervous system depression in 'Neurological') 524

Injection site pain 511

Injection site lump 501

Diarrhoea 493

Pain NOS 480

Panting 414

Elevated alanine aminotransferase (ALT) 349

Anorexia 313

Outcome Breakdown

Ongoing

4,207 (55.0%)

Outcome Unknown

1,957 (25.6%)

Recovered/Normal

874 (11.4%)

Died

281 (3.7%)

Recovered with Sequela

234 (3.1%)

Euthanized

95 (1.2%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.