Drug profile

The FDA adverse-event record for Bordetella Bronchiseptica, Modified Live, Avirulent Live Culture + Canine Parainfluenza Virus, Modified Live Virus, Avirulent Live Culture

76 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bordetella Bronchiseptica, Modified Live, Avirulent Live Culture + Canine Parainfluenza Virus, Modified Live Virus, Avirulent Live Culture. See the species affected, top reactions, and outcomes below.

76
adverse-event reports
6.6%
death-coded share
Dog
most-reported species
29
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
76
Total Reports
5
Deaths Reported
6.6%
Death Rate

Active Ingredients

Bordetella Bronchiseptica, Modified Live, Avirulent Live CultureCanine Parainfluenza Virus, Modified Live Virus, Avirulent Live Culture

Administration Routes

NasalUnknownSubcutaneous

Species Affected

Dog 76

Most Affected Breeds

Chihuahua 6
Crossbred Canine/dog 6
Pit Bull 6
Retriever - Labrador 4
Dog (other) 4
Shih Tzu 4
Bulldog 3
Maltese 3
Shepherd Dog - Australian 3
Spaniel - King Charles Cavalier 3

Most Reported Reactions

Vomiting 29
Lethargy (see also Central nervous system depression in Neurological) 13
Lethargy (see also Central nervous system depression in 'Neurological') 10
Diarrhoea 9
Not eating 7
Seizure NOS 7
Elevated alanine aminotransferase (ALT) 5
Dry mucous membrane 5
Neutrophilia 5
Abnormal radiograph finding 4
Ataxia 4
Anorexia 4

Outcome Breakdown

Outcome Unknown
35 (46.1%)
Recovered/Normal
29 (38.2%)
Ongoing
7 (9.2%)
Died
3 (3.9%)
Euthanized
2 (2.6%)

Bordetella Bronchiseptica, Modified Live, Avirulent Live Culture + Canine Parainfluenza Virus, Modified Live Virus, Avirulent Live Culture Adverse Event Insights

76 reports name Bordetella Bronchiseptica, Modified Live, Avirulent Live Culture + Canine Parainfluenza Virus, Modified Live Virus, Avirulent Live Culture; 5 recorded a death outcome (6.6% of reported events, not a population-level mortality rate). Active ingredients: Bordetella Bronchiseptica, Modified Live, Avirulent Live Culture, Canine Parainfluenza Virus, Modified Live Virus, Avirulent Live Culture. Administration routes: Nasal, Unknown, Subcutaneous.

By species: Dog (76 reports). By breed: Chihuahua (6), Crossbred Canine/dog (6), Pit Bull (6).

Leading clinical signs: Vomiting (29), Lethargy (see also Central nervous system depression in Neurological) (13), Lethargy (see also Central nervous system depression in 'Neurological') (10), Diarrhoea (9). Outcome, 76 coded reports: Outcome Unknown leads at 46.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.