Drug profile

The FDA adverse-event record for Oral Bordetella Vaccine

72 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Oral Bordetella Vaccine. See the species affected, top reactions, and outcomes below.

72
adverse-event reports
6.9%
death-coded share
Dog
most-reported species
22
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
72
Total Reports
5
Deaths Reported
6.9%
Death Rate

Active Ingredients

Oral Bordetella Vaccine

Administration Routes

OralUnknownSubcutaneous

Species Affected

Dog 72

Most Affected Breeds

Retriever - Labrador 14
Terrier (unspecified) 6
Terrier - Bull - American Pit 5
Retriever - Golden 4
Chihuahua 4
Terrier - Yorkshire 3
Bulldog - French 3
Collie - Border 3
Shepherd Dog - Australian 3
Maltese 2

Most Reported Reactions

Vomiting 22
Lethargy (see also Central nervous system depression in Neurological) 13
Anaphylaxis 9
Facial swelling (see also Skin) 8
Emesis (multiple) 7
Fever 6
Drooling 5
Pale mucous membrane 5
Abnormal radiograph finding 4
Diarrhoea 4
Lethargy (see also Central nervous system depression in 'Neurological') 4
Seizure NOS 4

Outcome Breakdown

Ongoing
31 (43.1%)
Recovered/Normal
28 (38.9%)
Outcome Unknown
7 (9.7%)
Died
3 (4.2%)
Euthanized
2 (2.8%)
Recovered with Sequela
1 (1.4%)

Oral Bordetella Vaccine Adverse Event Insights

72 reports name Oral Bordetella Vaccine; 5 recorded a death outcome (6.9% of reported events, not a population-level mortality rate). Active ingredient: Oral Bordetella Vaccine. Administration routes: Oral, Unknown, Subcutaneous.

By species: Dog (72 reports). By breed: Retriever - Labrador (14), Terrier (unspecified) (6), Terrier - Bull - American Pit (5).

Leading clinical signs: Vomiting (22), Lethargy (see also Central nervous system depression in Neurological) (13), Anaphylaxis (9), Facial swelling (see also Skin) (8). Outcome, 72 coded reports: Ongoing leads at 43.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.