Drug profile

The FDA adverse-event record for Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton

62 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton. Species, reactions, and outcomes follow.

#999 of 2,679
by report volume (all drugs)
62
adverse-event reports
6.5%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton ranks #994 of 2679 by total reports (62) and #718 of 1130 by death-coded share (6.5%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#994
This drug, reports of 2679
#718
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton has 62 reports now versus 62 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton changes

Signature read: death-coded share at 6.5% is the most distinctive stamp on Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
62
Total Reports
4
Deaths Reported
6.5%
Death-coded share of reports

Active Ingredients

Neomycin Sulfate Equivalent To Neomycin BaseNystatinThiostrepton

Administration Routes

UnknownAuricular (Otic)TopicalOphthalmic

Species Affected

Dog 50
Cat 12

Most Affected Breeds

Domestic Shorthair 7
Unknown 4
Bulldog - French 3
Retriever - Golden 3
Boxer (German Boxer) 3
Dog (unknown) 3
Maltese 3
Chihuahua 3
Poodle - Toy 2
Terrier (unspecified) 2

Most Reported Reactions

Deafness 34
Emesis 8
Impaired hearing 4
Ataxia 4
Lack of efficacy - NOS 3
Ear canal disorder 3
Incorrect route of drug administration 3
Accidental exposure 3
Partial deafness 3
Anorexia 3
Behavioural disorder NOS 3
Otorrhoea 2

Outcome Breakdown

Outcome Unknown
41 (66.1%)
Recovered/Normal
7 (11.3%)
Recovered with Sequela
6 (9.7%)
Ongoing
4 (6.5%)
Died
3 (4.8%)
Euthanized
1 (1.6%)

Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton (#999 of 2,679 by report volume); death-coded 6.5%. PlainBreed drug row · death-coded share stamp 6.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →