Drug profile

The FDA adverse-event record for Docp

140 FDA reports name Docp, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#649 of 2,679
by report volume (all drugs)
140
adverse-event reports
6.4%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Docp ranks #649 of 2679 by total reports (140) and #722 of 1130 by death-coded share (6.4%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#649
This drug, reports of 2679
#722
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Docp has 140 reports now versus 140 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Docp changes

Signature read: 140 reports place Docp in the upper third of FDA AER volume (#649 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
140
Total Reports
9
Deaths Reported
6.4%
Death-coded share of reports

Active Ingredients

Docp

Administration Routes

UnknownIntramuscularSubcutaneousIntravenousOtherParenteral

Species Affected

Dog 138
Cat 1
Goat 1

Most Affected Breeds

Retriever - Labrador 15
Poodle - Standard 9
Crossbred Canine/dog 7
Retriever - Golden 7
Chihuahua 6
Dog (unknown) 5
Pointing Dog - German Short-haired 5
Maltese 5
Shepherd Dog - German 5
Terrier (unspecified) 4

Most Reported Reactions

Immediate pain upon injection 41
High sodium-potassium ratio (Na:K ratio) 29
Vomiting 23
Diarrhoea 19
Lethargy (see also Central nervous system depression in 'Neurological') 17
Polyuria 15
Weight loss 11
Polydipsia 11
Elevated blood urea nitrogen (BUN) 10
Decreased appetite 10
Hyponatremia 8
Hypochloraemia 8

Outcome Breakdown

Recovered/Normal
65 (46.4%)
Outcome Unknown
51 (36.4%)
Ongoing
14 (10.0%)
Died
5 (3.6%)
Euthanized
4 (2.9%)
Recovered with Sequela
1 (0.7%)

Docp: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Docp, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Docp (#649 of 2,679 by report volume); death-coded 6.4%. PlainBreed drug row · report volume stamp 140 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →