Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
27
Total Reports
2
Deaths Reported
740.0%
Death Rate
6.6 yr
Avg Age at Report
Average weight at time of report: 12.4 kg (27.3 lbs)
Top Reported Reactions
Pain NOS 4
Lethargy (see also Central nervous system depression in 'Neurological') 4
Vomiting 3
Behavioural disorder NOS 3
Depression 3
Diarrhoea 3
Seizure NOS 3
Lack of efficacy (endoparasite) - hookworm 3
Tachypnoea 2
Thrombocytopenia 2
Lack of efficacy - NOS 2
Panting 2
Lack of efficacy (protozoa) - Coccidia 2
Lethargy (see also Central nervous system depression in Neurological) 2
Autoimmune disorder NOS 1
Most Referenced Drugs
Milbemycin Oxime + Spinosad 4
Afoxolaner 3
Milbemycin/Lufenuron Tablets 3
Milbemycin 2
Trilostane 2
Pyrantel Pamoate;Sarolaner 2
Ivermectin + Pyrantel As Pamoate Salt 2
Carprofen 1
Amoxicillin, Clavulanate 1
Amitraz 1
Selamectin 1
Cetirizine 1
Ivermectin 1
Prescription Diet (Unknown) 1
Oclacitinib Maleate 1
Outcome Breakdown
Recovered/Normal
10 (47.6%)
Ongoing
5 (23.8%)
Outcome Unknown
3 (14.3%)
Died
1 (4.8%)
Recovered with Sequela
1 (4.8%)
Euthanized
1 (4.8%)
Gender Distribution
Female 14 (51.9%)
Male 13 (48.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 5 | |
| 2012 | 3 | |
| 2014 | 4 | |
| 2016 | 1 | |
| 2018 | 2 | |
| 2019 | 1 | |
| 2020 | 1 | |
| 2021 | 3 | |
| 2022 | 2 | |
| 2023 | 3 | |
| 2024 | 1 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #327 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.