Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
17
Total Reports
0
Deaths Reported
0.0%
Death Rate
3.9 yr
Avg Age at Report
Average weight at time of report: 23.7 kg (52.3 lbs)
Top Reported Reactions
Lack of efficacy (endoparasite) - heartworm 4
INEFFECTIVE, HEARTWORM LARVAE 3
Lethargy (see also Central nervous system depression in 'Neurological') 2
Elevated blood urea nitrogen (BUN) 2
Elevated creatinine 2
Lack of efficacy (endoparasite) - roundworm NOS 2
Elevated alanine aminotransferase (ALT) 1
Elevated serum alkaline phosphatase (SAP) 1
Lack of efficacy (endoparasite) - hookworm 1
Anorexia 1
Renal failure 1
Malaise 1
Labeled drug-species interaction 1
Walking difficulty 1
Inappetence 1
Most Referenced Drugs
Milbemycin Oxime + Spinosad 4
Milbemycin Oxime, Lufenuron 3
Lufenuron + Milbemycin Oxime 3
Milbemycin Oxime + Praziquantel 2
Spinosad 1
Milbemycin Oxime 1
Ivermectin 0.5% Pour-On Topical Solution 1
Cephalexin 1
Fluralaner Chew Tablets 1
Fluralaner 1
Lufenuron + Milbemycin Oxime + Praziquantel 1
Ivermectin + Pyrantel Pamoate 1
Moxidectin 1
Pyrantel Pamoate;Sarolaner 1
Outcome Breakdown
Outcome Unknown
12 (70.6%)
Ongoing
3 (17.6%)
Recovered/Normal
2 (11.8%)
Gender Distribution
Female 8 (47.1%)
Male 8 (47.1%)
Mixed 1 (5.9%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 1 | |
| 2013 | 1 | |
| 2015 | 1 | |
| 2016 | 3 | |
| 2017 | 3 | |
| 2018 | 1 | |
| 2019 | 1 | |
| 2020 | 3 | |
| 2023 | 3 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #382 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.