Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
21
Total Reports
4
Deaths Reported
1900.0%
Death Rate
5.7 yr
Avg Age at Report
Average weight at time of report: 18.0 kg (39.7 lbs)
Top Reported Reactions
Vomiting 7
Diarrhoea 5
Lack of efficacy (endoparasite) - heartworm 4
Death by euthanasia 3
Loose stool 3
Tense abdomen 3
Lethargy (see also Central nervous system depression in Neurological) 3
Lung sound 3
Decreased appetite 2
Monocytosis 2
Increased respiratory rate 2
Low platelet count 2
Hypochloraemia 2
Eye redness 2
Decreased haematocrit 2
Most Referenced Drugs
Enrofloxacin 5
Oclacitinib Maleate 4
Milbemycin Oxime + Spinosad 3
Milbemycin Oxime + Praziquantel 3
Fluralaner 13.64% 12-Week Chew 3
Ivermectin + Pyrantel As Pamoate Salt 3
Ilunocitinib 3
S-Adenosyl-L-Methionine-Tosylate Disulfate 3
Dexamethasone 3
Pentoxifylline 3
Afoxolaner 3
Hydrolyzed Protein Diet 3
Trazodone 3
Shampoo 3
Skin Conditioner (Unknown) 3
Outcome Breakdown
Recovered/Normal
7 (33.3%)
Ongoing
6 (28.6%)
Outcome Unknown
4 (19.0%)
Euthanized
3 (14.3%)
Died
1 (4.8%)
Gender Distribution
Male 13 (61.9%)
Female 8 (38.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 1 | |
| 2017 | 3 | |
| 2018 | 2 | |
| 2019 | 4 | |
| 2021 | 1 | |
| 2022 | 6 | |
| 2024 | 1 | |
| 2025 | 3 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #354 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.