Total Reports
197
FDA CVM filings
Dog /
FDA CVM · 2025 release 197 reports on file
Terrier - American Staffordshire - FDA Adverse Event Profile
Adverse-event records for Terrier - American Staffordshire (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Terrier - American Staffordshire ranks #184 by report volume among dog breeds - 4 of 197 reports (2.0%) recorded a death outcome.
- #184
- most-reported dog breed
- 2.0%
- death-coded report share
- 52
- Lack of efficacy (endoparasite) - heartworm - top reaction
- 5.0 yr
- average age at report
Higher volume usually means a more popular breed, not a riskier one, compare against how common the breed is.
Deaths Reported
4
of 197 reports
Death Rate
2.0%
death-coded share
Avg Age at Report
5.0 yr
27.0 kg avg weight
Death-Coded Outcome Share
Terrier - American Staffordshire death-coded reports 2.0%
Cross-breed median
2.0% of 197 terrier - american staffordshire reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 27.0 kg (59.5 lbs)
Top Reported Reactions
Lack of efficacy (endoparasite) - heartworm 52
Vomiting 27
Lack of efficacy (ectoparasite) - flea 18
Diarrhoea 14
Not eating 12
Lack of efficacy (endoparasite) - hookworm 10
Lethargy (see also Central nervous system depression in Neurological) 10
Lethargy (see also Central nervous system depression in 'Neurological') 9
Most Referenced Drugs
Milbemycin Oxime + Spinosad 54
Milbemycin Oxime + Praziquantel 45
Ivermectin + Pyrantel As Pamoate Salt 21
Lotilaner 17
Fluralaner 13.64% 12-Week Chew 14
Gabapentin 11
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 10
Oclacitinib Maleate 9
Outcome Breakdown
Outcome Unknown
100 (50.8%)
Ongoing
54 (27.4%)
Recovered/Normal
36 (18.3%)
Recovered with Sequela
3 (1.5%)
Euthanized
2 (1.0%)
Died
2 (1.0%)
Gender Distribution
Female 103 (52.3%)
Male 92 (46.7%)
Unknown 2 (1.0%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2016 | 1 | |
| 2017 | 1 | |
| 2018 | 14 | |
| 2019 | 10 | |
| 2020 | 26 | |
| 2021 | 15 | |
| 2022 | 36 | |
| 2023 | 33 | |
| 2024 | 35 | |
| 2025 | 26 | |
Terrier - American Staffordshire Pet Health Insights
Terrier - American Staffordshire accounts for 197 FDA adverse event reports, ranking #184 by volume among dog breeds, with 4 reports (2.0%) coded as a death outcome. Mean age at report: 5.0 years, average weight 27.0 kg (59.5 lbs).
Top reported signs: Lack of efficacy (endoparasite) - heartworm (52), Vomiting (27), Lack of efficacy (ectoparasite) - flea (18). Most-referenced drug: Milbemycin Oxime + Spinosad (54 reports), followed by Milbemycin Oxime + Praziquantel (45) and Ivermectin + Pyrantel As Pamoate Salt (21).
Outcome coding on 197 status-recorded reports is dominated by Outcome Unknown (50.8%). Annual submissions ranged 2,016-2,025 across 10 years on file.
Dog Breeds With a Similar Report Volume
Greater Swiss Mountain Dog
187 reports · 3.2% death rate
Coonhound - Redbone
210 reports · 3.8% death rate
Pointer - English Pointer
179 reports · 8.9% death rate
Treeing Feist
215 reports · 1.9% death rate
Griffon - French Wire-haired Pointing
218 reports · 0.5% death rate
Terrier - Irish
176 reports · 2.3% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Terrier - American Staffordshire? ▼
There are 197 adverse event reports involving Terrier - American Staffordshire in the FDA database, with 4 reports involving death (2.0% death rate). Terrier - American Staffordshire ranks #184 by report volume.
What are the most common adverse reactions reported for Terrier - American Staffordshire? ▼
The most commonly reported adverse reactions for Terrier - American Staffordshire are Lack of efficacy (endoparasite) - heartworm (52 reports), Vomiting (27 reports), Lack of efficacy (ectoparasite) - flea (18 reports), Diarrhoea (14 reports), Not eating (12 reports).
What drugs are most frequently associated with Terrier - American Staffordshire adverse events? ▼
The drugs most frequently referenced in Terrier - American Staffordshire adverse event reports are Milbemycin Oxime + Spinosad (54 reports), Milbemycin Oxime + Praziquantel (45 reports), Ivermectin + Pyrantel As Pamoate Salt (21 reports), Lotilaner (17 reports), Fluralaner 13.64% 12-Week Chew (14 reports).
What is the average age of Terrier - American Staffordshire in adverse event reports? ▼
The average age of Terrier - American Staffordshire at the time of adverse event reports is 5.0 years, with an average weight of 27.0 kg (59.5 lbs).
Does a high number of adverse event reports mean Terrier - American Staffordshire is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Terrier - American Staffordshire safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.