Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
33
Total Reports
1
Deaths Reported
300.0%
Death Rate
4.8 yr
Avg Age at Report
Average weight at time of report: 31.0 kg (68.4 lbs)
Top Reported Reactions
Diarrhoea 6
Emesis 5
Lethargy (see also Central nervous system depression in 'Neurological') 4
Digestive tract disorder NOS 3
Seizure NOS 3
Vomiting 2
Lack of efficacy (endoparasite) - hookworm 2
Not eating 2
Paddling 2
Opisthotonus 2
Behavioural disorder NOS 2
Pruritus 2
Hair loss NOS 2
Lack of efficacy (ectoparasite) - flea 2
Lack of efficacy (endoparasite) - heartworm 2
Most Referenced Drugs
Ivermectin + Pyrantel As Pamoate Salt 5
Afoxolaner 4
Milbemycin Oxime + Spinosad 3
Moxidectin 3
Sarolaner 3
Milbemycin 2
Spinosad 2
Maropitant Citrate 2
Propofol 2
Buprenorphine 2
Grapiprant 2
Imidacloprid + Moxidectin 2
Selamectin 1
Ivermectin 272Mcg, Pyrantel Pamoate 228Mg, Praziquantel 228Mg 1
Ivermectin/Pyrantel Pamoate Chewable 136Mcg/326Mg 1
Outcome Breakdown
Recovered/Normal
13 (43.3%)
Outcome Unknown
10 (33.3%)
Ongoing
6 (20.0%)
Died
1 (3.3%)
Gender Distribution
Female 18 (54.5%)
Male 15 (45.5%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 1 | |
| 2011 | 2 | |
| 2012 | 4 | |
| 2013 | 2 | |
| 2014 | 3 | |
| 2015 | 3 | |
| 2016 | 3 | |
| 2017 | 1 | |
| 2018 | 3 | |
| 2019 | 4 | |
| 2020 | 2 | |
| 2021 | 1 | |
| 2023 | 1 | |
| 2024 | 2 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #306 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.