Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
33
Total Reports
1
Deaths Reported
300.0%
Death Rate
5.1 yr
Avg Age at Report
Average weight at time of report: 29.7 kg (65.5 lbs)
Top Reported Reactions
Lack of efficacy (endoparasite) - heartworm 6
Lethargy (see also Central nervous system depression in 'Neurological') 4
Vomiting 3
Anorexia 3
Seizure NOS 3
Lack of efficacy (ectoparasite) - flea 3
Emesis 2
INEFFECTIVE, ASCARIDS NOS 2
Panting 2
Restlessness 2
Vocalisation 2
Lack of efficacy (bacteria) - NOS 2
Lack of efficacy (tick) 2
UNPALATABLE 1
Odor, Abnormal 1
Most Referenced Drugs
Moxidectin 5
Ivermectin + Pyrantel As Pamoate Salt 4
Afoxolaner 4
Spinosad 3
Ivermectin 3
Milbemycin Oxime + Praziquantel 3
Pyrantel Pamoate;Sarolaner 3
Bedinvetmab 3
Milbemycin Oxime + Spinosad 2
Rabies Virus, Kv 2
Sarolaner 2
Praziquantel 2
Nitenpyram 2
Gentamicin + Mometasone + Clotrimazole 1
Leptospira Canicola L-15 Strain C-51; Leptospira Grippotyphosa 1550 Lot 10005 St 1
Outcome Breakdown
Ongoing
13 (39.4%)
Outcome Unknown
10 (30.3%)
Recovered/Normal
9 (27.3%)
Died
1 (3.0%)
Gender Distribution
Male 18 (54.5%)
Female 15 (45.5%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 1 | |
| 2013 | 1 | |
| 2014 | 1 | |
| 2015 | 2 | |
| 2017 | 3 | |
| 2018 | 1 | |
| 2019 | 4 | |
| 2020 | 1 | |
| 2021 | 2 | |
| 2022 | 3 | |
| 2023 | 6 | |
| 2024 | 6 | |
| 2025 | 2 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #310 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.