Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
33
Total Reports
1
Deaths Reported
300.0%
Death Rate
4.7 yr
Avg Age at Report
Average weight at time of report: 42.1 kg (92.8 lbs)
Top Reported Reactions
Vomiting 7
INEFFECTIVE, HEARTWORM LARVAE 4
Diarrhoea 4
Lack of efficacy (endoparasite) - heartworm 3
Panting 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Seizure NOS 2
Hypersalivation 2
Drooling 2
No sign 1
Dermatitis 1
Other abnormal test result NOS 1
Gingivitis 1
Melanoma 1
Skin and/or appendage neoplasm NOS 1
Most Referenced Drugs
Ivermectin + Pyrantel As Pamoate Salt 4
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 3
Fluralaner Chew Tablets 3
Imidacloprid + Moxidectin 3
Fluralaner 13.64% 12-Week Chew 3
Milbemycin Oxime, Lufenuron 2
Afoxolaner 136 Mg Chewable Tablets 2
Oclacitinib Maleate 2
Imepitoin 2
Cyclosporine A 1
Levothyroxine 1
Fish Oil 1
Ivermectin 272Mcg, Pyrantel 227Mg 1
Cyclosporine 1
Cephalexin 1
Outcome Breakdown
Recovered/Normal
15 (45.5%)
Outcome Unknown
14 (42.4%)
Ongoing
3 (9.1%)
Euthanized
1 (3.0%)
Gender Distribution
Female 19 (57.6%)
Male 14 (42.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2011 | 1 | |
| 2012 | 1 | |
| 2014 | 1 | |
| 2015 | 4 | |
| 2016 | 5 | |
| 2017 | 4 | |
| 2018 | 1 | |
| 2019 | 1 | |
| 2021 | 4 | |
| 2022 | 6 | |
| 2023 | 3 | |
| 2024 | 1 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #309 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.