Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
28
Total Reports
2
Deaths Reported
710.0%
Death Rate
5.0 yr
Avg Age at Report
Average weight at time of report: 45.5 kg (100.3 lbs)
Top Reported Reactions
Vomiting 7
Lack of efficacy (ectoparasite) - flea 4
Dermal mass 3
Mast cell tumour 3
Drooling 2
Hives (see also 'Skin') 2
Weight loss 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Inappetence 2
Seizure NOS 2
Death by euthanasia 2
Anxiety 2
Lack of efficacy (ectoparasite) - tick NOS 2
Panting 2
Diarrhoea 2
Most Referenced Drugs
Milbemycin Oxime + Spinosad 5
Fluralaner Chew Tablets 5
Cyclosporine 3
Imidacloprid, Flumethrin 3
Ketoconazole 3
Vitamin A 3
Moxidectin 3
Carprofen 2
Grapiprant 2
Shampoo 2
Skin Conditioner (Unknown) 2
Fluralaner 2
Pyrantel Pamoate;Sarolaner 2
Fluralaner 13.64% 12-Week Chew 2
Bedinvetmab 2
Outcome Breakdown
Ongoing
11 (39.3%)
Recovered/Normal
8 (28.6%)
Outcome Unknown
5 (17.9%)
Recovered with Sequela
2 (7.1%)
Euthanized
2 (7.1%)
Gender Distribution
Male 15 (53.6%)
Female 13 (46.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2011 | 1 | |
| 2012 | 1 | |
| 2014 | 3 | |
| 2015 | 3 | |
| 2016 | 3 | |
| 2018 | 2 | |
| 2019 | 1 | |
| 2020 | 4 | |
| 2021 | 3 | |
| 2022 | 4 | |
| 2023 | 1 | |
| 2024 | 1 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #324 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.