Total Reports
28
FDA CVM filings
Dog /
FDA CVM · 2025 release 28 reports on file
Mastiff - Tibetan - FDA Adverse Event Profile
Adverse-event records for Mastiff - Tibetan (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
With 28 reports on file, Mastiff - Tibetan sits at #324 among dog breeds by volume; death-coded share is 7.1% (2 reports).
- #324
- most-reported dog breed
- 7.1%
- death-coded report share
- 7
- Vomiting - top reaction
- 5.0 yr
- average age at report
Report counts track breed popularity and reporting activity, not real-world risk, read this alongside how common the breed is.
Deaths Reported
2
of 28 reports
Death Rate
7.1%
death-coded share
Avg Age at Report
5.0 yr
45.5 kg avg weight
Death-Coded Outcome Share
Mastiff - Tibetan death-coded reports 7.1%
Cross-breed median
7.1% of 28 mastiff - tibetan reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 45.5 kg (100.3 lbs)
Top Reported Reactions
Vomiting 7
Lack of efficacy (ectoparasite) - flea 4
Dermal mass 3
Mast cell tumour 3
Drooling 2
Most Referenced Drugs
Milbemycin Oxime + Spinosad 5
Fluralaner Chew Tablets 5
Cyclosporine 3
Imidacloprid, Flumethrin 3
Ketoconazole 3
Outcome Breakdown
Ongoing
11 (39.3%)
Recovered/Normal
8 (28.6%)
Outcome Unknown
5 (17.9%)
Recovered with Sequela
2 (7.1%)
Euthanized
2 (7.1%)
Gender Distribution
Male 15 (53.6%)
Female 13 (46.4%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2011 | 1 | |
| 2012 | 1 | |
| 2014 | 3 | |
| 2015 | 3 | |
| 2016 | 3 | |
| 2018 | 2 | |
| 2019 | 1 | |
| 2020 | 4 | |
| 2021 | 3 | |
| 2022 | 4 | |
| 2023 | 1 | |
| 2024 | 1 | |
| 2025 | 1 | |
Mastiff - Tibetan Pet Health Insights
Mastiff - Tibetan accounts for 28 FDA adverse event reports, ranking #324 by volume among dog breeds, with 2 reports (7.1%) coded as a death outcome. Mean age at report: 5.0 years, average weight 45.5 kg (100.3 lbs).
Top reported signs: Vomiting (7), Lack of efficacy (ectoparasite) - flea (4), Dermal mass (3). Most-referenced drug: Milbemycin Oxime + Spinosad (5 reports), followed by Fluralaner Chew Tablets (5) and Cyclosporine (3).
Outcome coding on 28 status-recorded reports is dominated by Ongoing (39.3%). Annual submissions ranged 2,011-2,025 across 13 years on file.
Dog Breeds With a Similar Report Volume
Basset - Griffon Vendeen Small
28 reports · 7.1% death rate
Sheepdog - Maremma and Abruzzes
28 reports · 0.0% death rate
Terrier - Black Russian
28 reports · 0.0% death rate
Terrier - Skye
28 reports · 3.6% death rate
Deerhound - scottish
29 reports · 20.7% death rate
Terrier - Dandie Dinmont
27 reports · 3.7% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Mastiff - Tibetan? ▼
There are 28 adverse event reports involving Mastiff - Tibetan in the FDA database, with 2 reports involving death (7.1% death rate). Mastiff - Tibetan ranks #324 by report volume.
What are the most common adverse reactions reported for Mastiff - Tibetan? ▼
The most commonly reported adverse reactions for Mastiff - Tibetan are Vomiting (7 reports), Lack of efficacy (ectoparasite) - flea (4 reports), Dermal mass (3 reports), Mast cell tumour (3 reports), Drooling (2 reports).
What drugs are most frequently associated with Mastiff - Tibetan adverse events? ▼
The drugs most frequently referenced in Mastiff - Tibetan adverse event reports are Milbemycin Oxime + Spinosad (5 reports), Fluralaner Chew Tablets (5 reports), Cyclosporine (3 reports), Imidacloprid, Flumethrin (3 reports), Ketoconazole (3 reports).
What is the average age of Mastiff - Tibetan in adverse event reports? ▼
The average age of Mastiff - Tibetan at the time of adverse event reports is 5.0 years, with an average weight of 45.5 kg (100.3 lbs).
Does a high number of adverse event reports mean Mastiff - Tibetan is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Mastiff - Tibetan safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.