Total Reports
44
FDA CVM filings
Dog /
FDA CVM · 2025 release 44 reports on file
Puli - FDA Adverse Event Profile
Adverse-event records for Puli (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Puli ranks #276 by report volume among dog breeds - 0 of 44 reports (0.0%) recorded a death outcome.
- #276
- most-reported dog breed
- 0.0%
- death-coded report share
- 11
- Vomiting - top reaction
- 5.9 yr
- average age at report
Higher volume usually means a more popular breed, not a riskier one, compare against how common the breed is.
Deaths Reported
0
of 44 reports
Death Rate
0.0%
death-coded share
Avg Age at Report
5.9 yr
13.7 kg avg weight
Death-Coded Outcome Share
Puli death-coded reports 0.0%
Cross-breed median
0.0% of 44 puli reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 13.7 kg (30.2 lbs)
Top Reported Reactions
Vomiting 11
Diarrhoea 8
Lack of efficacy (ectoparasite) - flea 6
Restlessness 5
Lethargy (see also Central nervous system depression in 'Neurological') 5
Most Referenced Drugs
Milbemycin Oxime + Spinosad 10
Spinosad 6
Milbemycin Oxime 4
Ivermectin + Pyrantel As Pamoate Salt 4
Cyclosporine 2
Outcome Breakdown
Outcome Unknown
20 (47.6%)
Recovered/Normal
14 (33.3%)
Ongoing
6 (14.3%)
Recovered with Sequela
2 (4.8%)
Gender Distribution
Female 22 (50.0%)
Male 21 (47.7%)
Unknown 1 (2.3%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 2 | |
| 2011 | 1 | |
| 2012 | 1 | |
| 2013 | 2 | |
| 2014 | 5 | |
| 2015 | 6 | |
| 2016 | 9 | |
| 2017 | 1 | |
| 2018 | 1 | |
| 2019 | 2 | |
| 2020 | 3 | |
| 2021 | 4 | |
| 2022 | 2 | |
| 2023 | 1 | |
| 2024 | 4 | |
Puli Pet Health Insights
Puli accounts for 44 FDA adverse event reports, ranking #276 by volume among dog breeds, with 0 reports (0.0%) coded as a death outcome. Mean age at report: 5.9 years, average weight 13.7 kg (30.2 lbs).
Top reported signs: Vomiting (11), Diarrhoea (8), Lack of efficacy (ectoparasite) - flea (6). Most-referenced drug: Milbemycin Oxime + Spinosad (10 reports), followed by Spinosad (6) and Milbemycin Oxime (4).
Outcome coding on 42 status-recorded reports is dominated by Outcome Unknown (47.6%). Annual submissions ranged 2,010-2,024 across 15 years on file.
Dog Breeds With a Similar Report Volume
Frequently Asked Questions
How many FDA adverse event reports involve Puli? ▼
There are 44 adverse event reports involving Puli in the FDA database, with 0 reports involving death (0.0% death rate). Puli ranks #276 by report volume.
What are the most common adverse reactions reported for Puli? ▼
The most commonly reported adverse reactions for Puli are Vomiting (11 reports), Diarrhoea (8 reports), Lack of efficacy (ectoparasite) - flea (6 reports), Restlessness (5 reports), Lethargy (see also Central nervous system depression in 'Neurological') (5 reports).
What drugs are most frequently associated with Puli adverse events? ▼
The drugs most frequently referenced in Puli adverse event reports are Milbemycin Oxime + Spinosad (10 reports), Spinosad (6 reports), Milbemycin Oxime (4 reports), Ivermectin + Pyrantel As Pamoate Salt (4 reports), Cyclosporine (2 reports).
What is the average age of Puli in adverse event reports? ▼
The average age of Puli at the time of adverse event reports is 5.9 years, with an average weight of 13.7 kg (30.2 lbs).
Does a high number of adverse event reports mean Puli is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Puli safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.