Dog /
2026 FDA CVM data 17 reports on file official source

Leopard Cur — FDA Adverse Event Profile

Adverse-event records and label data for Leopard Cur (Dog), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.

Verify with FDA CVM →
Annual breed adverse-event registration timeline Bar chart showing yearly FDA Center for Veterinary Medicine adverse event report counts per breed registry cohort, with paw-print tick marks indicating count buckets. 6 4.5 3 1.5 0 2017 2018 2019 2020 2021 2022 2023 2024 Reports filed Death-coded reports
Annual report volume for Leopard Cur drawn from FDA CVM filings.

Leopard Cur (Dog) has 17 FDA adverse event reports on record, with 0 deaths reported (0.0% death rate) — ranking #384 by report volume. The most frequently reported reaction is Lack of efficacy (endoparasite) - heartworm (6 cases). The top associated drug is Milbemycin Oxime + Praziquantel. Average age at report: 3.3 years.

Total Reports

17

FDA CVM filings

Deaths Reported

0

of 17 reports

Death Rate

0.0%

death-coded share

Avg Age at Report

3.3 yr

25.6 kg avg weight

Death-Coded Outcome Share

Leopard Cur death-coded reports 0.0%
Database median

0.0% of 17 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 25.6 kg (56.4 lbs)

Top Reported Reactions

Lack of efficacy (endoparasite) - heartworm 6
Lack of efficacy (endoparasite) - hookworm 3
Lack of efficacy (ectoparasite) - flea 2
Emesis 1
Agitation 1
INEFFECTIVE, HEARTWORM LARVAE 1
Blistering (see also Application site SOC) 1
Hives (see also 'Skin') 1
Generalised rash 1
Vomiting 1
Blood in vomit 1
Drooling 1
Bloody diarrhoea 1
Inappetence 1
Pica NOS 1

Most Referenced Drugs

Milbemycin Oxime + Praziquantel 8
Milbemycin Oxime + Spinosad 5
Moxidectin 4
Melarsomine Dihydrochloride 2
Melarsomine 2
Lotilaner 2
Febantel + Praziquantel + Pyrantel 2
Pyrantel 2
Spinosad 2
Nitenpyram 1
Rabies Vaccine 1
Prednisone 1
Pyrantel Pamoate;Sarolaner 1
Sarolaner 1
Recombinant E. Coli Bl21;Recombinant E. Coli Ecl19 1

Outcome Breakdown

Outcome Unknown
9 (52.9%)
Ongoing
6 (35.3%)
Recovered/Normal
2 (11.8%)

Gender Distribution

Female 10 (58.8%)
Male 6 (35.3%)
Unknown 1 (5.9%)

Reports by Year

Year Reports Trend
2012 1
2016 1
2017 1
2018 1
2019 1
2020 1
2021 2
2022 6
2023 2
2024 1
Size-class weight distribution across registered breeds Vertical bar chart showing the distribution of registered breeds across five size classes (Toy, Small, Medium, Large, Giant), each represented by a scaled dog-silhouette and a count value. 118 89 59 30 0 Breeds in class 38 Toy 0–6 kg Chihuahua 64 Small 6–14 kg Beagle 92 Medium 14–27 kg Border Collie 118 Large 27–45 kg Labrador Retriever 41 Giant 45–90 kg Great Dane Size-Class Distribution
Where Leopard Cur sits in the registered size-class taxonomy. Average reported weight: 25.6 kg.
Breed-group distribution donut chart Donut chart with kennel-club-ribbon center showing breed counts across the eight standard breed groups (Sporting, Hound, Working, Terrier, Toy, Non-Sporting, Herding, Miscellaneous). CH Sporting 32 · 14.2% Hound 36 · 15.9% Working 33 · 14.6% Terrier 31 · 13.7% Toy 23 · 10.2% Non-Sporting 21 · 9.3% Herding 32 · 14.2% Misc. 18 · 8.0% Breed-Group Classification 226 breeds across 8 taxonomic groups
Eight standard breed-group classifications used by major registries (AKC's seven groups plus Miscellaneous). Provides taxonomic context for breed lookups.

Leopard Cur Pet Health Insights

Across the FDA Center for Veterinary Medicine adverse event database, Leopard Cur accounts for 17 submitted reports and currently ranks #384 by report volume within the dog population. Of those reports, 0 involved a death outcome — a 0.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 3.3 years, with an average recorded body weight of 25.6 kg (56.4 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.

The most frequently reported clinical signs for Leopard Cur are Lack of efficacy (endoparasite) - heartworm (6 reports), Lack of efficacy (endoparasite) - hookworm (3 reports), Lack of efficacy (ectoparasite) - flea (2 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Milbemycin Oxime + Praziquantel appears in 8 reports and is the single most-referenced drug, followed by Milbemycin Oxime + Spinosad (5) and Moxidectin (4). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same dog species.

Outcome coding on the 17 reports with a recorded status is dominated by Outcome Unknown (52.9% of coded outcomes). Annual submission volume ranges from 2,012 to 2,024 reports across the 10 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual dog.

Understanding Leopard Cur Adverse Event Data

Leopard Cur has 17 adverse event reports on file. Lower report volumes may reflect a less common breed, lower reporting rates, or genuinely fewer adverse events.

A 0.0% death rate is below average in the FDA adverse event database, suggesting reported events tend toward less severe outcomes.

The most frequently referenced drug in adverse reports is Milbemycin Oxime + Praziquantel, appearing in 8 reports. This may indicate widespread use of the medication rather than a specific safety concern for Leopard Cur.

Other Dog Breeds

Frequently Asked Questions

How many FDA adverse event reports involve Leopard Cur?
There are 17 adverse event reports involving Leopard Cur in the FDA database, with 0 reports involving death (0.0% death rate). Leopard Cur ranks #384 by report volume.
What are the most common adverse reactions reported for Leopard Cur?
The most commonly reported adverse reactions for Leopard Cur are Lack of efficacy (endoparasite) - heartworm (6 reports), Lack of efficacy (endoparasite) - hookworm (3 reports), Lack of efficacy (ectoparasite) - flea (2 reports), Emesis (1 reports), Agitation (1 reports).
What drugs are most frequently associated with Leopard Cur adverse events?
The drugs most frequently referenced in Leopard Cur adverse event reports are Milbemycin Oxime + Praziquantel (8 reports), Milbemycin Oxime + Spinosad (5 reports), Moxidectin (4 reports), Melarsomine Dihydrochloride (2 reports), Melarsomine (2 reports).
What is the average age of Leopard Cur in adverse event reports?
The average age of Leopard Cur at the time of adverse event reports is 3.3 years, with an average weight of 25.6 kg (56.4 lbs).
Does a high number of adverse event reports mean Leopard Cur is unhealthy?
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Leopard Cur safety data come from?
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.

Guides & Resources

Related Data Sources

Data Sources & Methodology

Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.

Leopard Cur ranks #384 by total report volume. Death rate (0.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial