Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
44
Total Reports
6
Deaths Reported
1360.0%
Death Rate
5.5 yr
Avg Age at Report
Average weight at time of report: 41.5 kg (91.5 lbs)
Top Reported Reactions
Vomiting 8
Lack of efficacy - NOS 7
Anorexia 6
Death 5
Diarrhoea 5
Lethargy (see also Central nervous system depression in 'Neurological') 4
Bloody diarrhoea 3
Depression 3
Lack of efficacy (ectoparasite) - flea 3
Pruritus 3
INEFFECTIVE, ASCARIDS NOS 3
Hot spot (pyotraumatic dermatitis) 3
Cardiac arrest 2
Icterus 2
Nausea 2
Most Referenced Drugs
Milbemycin Oxime + Spinosad 11
Ivermectin + Pyrantel As Pamoate Salt 7
Afoxolaner 6
Spinosad 4
Carprofen 3
Oclacitinib Maleate 3
Pyrantel Pamoate;Sarolaner 3
Fluralaner Chew Tablets 2
Milbemycin Oxime + Praziquantel 2
Prednisone 2
Fluoxetine 1
Firocoxib 1
Selamectin 1
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 1
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 1
Outcome Breakdown
Recovered/Normal
14 (33.3%)
Outcome Unknown
13 (31.0%)
Ongoing
6 (14.3%)
Died
5 (11.9%)
Recovered with Sequela
3 (7.1%)
Euthanized
1 (2.4%)
Gender Distribution
Male 23 (52.3%)
Female 20 (45.5%)
Mixed 1 (2.3%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 4 | |
| 2011 | 3 | |
| 2013 | 3 | |
| 2014 | 4 | |
| 2015 | 3 | |
| 2016 | 9 | |
| 2017 | 2 | |
| 2018 | 4 | |
| 2019 | 3 | |
| 2020 | 3 | |
| 2021 | 2 | |
| 2022 | 1 | |
| 2023 | 1 | |
| 2024 | 2 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #279 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.