Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
40
Total Reports
1
Deaths Reported
250.0%
Death Rate
4.7 yr
Avg Age at Report
Average weight at time of report: 19.6 kg (43.2 lbs)
Top Reported Reactions
Lethargy (see also Central nervous system depression in 'Neurological') 8
Vomiting 5
Lack of efficacy - NOS 4
INEFFECTIVE, ASCARIDS NOS 4
Lack of efficacy (endoparasite) - heartworm 4
Digestive tract disorder NOS 3
Seizure NOS 3
Neurological signs NOS 2
Shaking 2
Panting 2
Lack of efficacy (endoparasite) - hookworm 2
Polydipsia 2
Urinary incontinence 2
Anorexia 2
Leucocytosis NOS 2
Most Referenced Drugs
Milbemycin Oxime + Spinosad 8
Oclacitinib Maleate 6
Moxidectin 6
Sarolaner 4
Carprofen 4
Pyrantel Pamoate;Sarolaner 4
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 3
Afoxolaner 3
Selamectin 2
Ivermectin + Pyrantel As Pamoate Salt 2
Amoxicillin (As Trihydrate); Clavulanate Potassium ( K-Clavulanate) 2
Bordetella Bronchiseptica, Strain 78-9159, Kb 2
Ivermectin + Pyrantel 2
Canine Distemper + Adenovirus Type 2 + Parainfluenza + Parvovirus Vaccine 2
Rabies Virus Vaccine 2
Outcome Breakdown
Ongoing
16 (40.0%)
Outcome Unknown
12 (30.0%)
Recovered/Normal
11 (27.5%)
Euthanized
1 (2.5%)
Gender Distribution
Male 25 (62.5%)
Female 15 (37.5%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 3 | |
| 2013 | 1 | |
| 2014 | 3 | |
| 2015 | 2 | |
| 2016 | 3 | |
| 2017 | 7 | |
| 2018 | 1 | |
| 2019 | 2 | |
| 2020 | 4 | |
| 2021 | 5 | |
| 2022 | 2 | |
| 2023 | 1 | |
| 2024 | 3 | |
| 2025 | 3 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #290 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.