Total Reports
615
FDA CVM filings
Dog /
FDA CVM · 2025 release 615 reports on file
Griffon - Brussels - FDA Adverse Event Profile
Adverse-event records for Griffon - Brussels (Dog) from the FDA Center for Veterinary Medicine.
Data updated June 2026
The record at a glance
Among dog breeds, Griffon - Brussels is #128 by FDA report volume; 5.0% of its 615 reports (31) were death-coded.
- #128
- most-reported dog breed
- 5.0%
- death-coded report share
- 158
- Vomiting - top reaction
- 6.7 yr
- average age at report
Higher volume usually means a more popular breed, not a riskier one, compare against how common the breed is.
Deaths Reported
31
of 615 reports
Death Rate
5.0%
death-coded share
Avg Age at Report
6.7 yr
7.1 kg avg weight
Death-Coded Outcome Share
Griffon - Brussels death-coded reports 5.0%
Cross-breed median
5.0% of 615 griffon - brussels reports involved a death outcome.
How to read this number
Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (about 4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 7.1 kg (15.7 lbs)
Top Reported Reactions
Vomiting 158
Lethargy (see also Central nervous system depression in 'Neurological') 60
Diarrhoea 55
Emesis 54
Lack of efficacy - NOS 42
Other abnormal test result NOS 27
Seizure NOS 27
Ataxia 24
Most Referenced Drugs
Milbemycin Oxime + Spinosad 102
Ivermectin + Pyrantel As Pamoate Salt 48
Afoxolaner 37
Spinosad 35
Fluralaner Chew Tablets 34
Trilostane 32
Oclacitinib Maleate 32
Moxidectin 27
Outcome Breakdown
Recovered/Normal
211 (37.0%)
Outcome Unknown
161 (28.2%)
Ongoing
146 (25.6%)
Recovered with Sequela
22 (3.9%)
Euthanized
17 (3.0%)
Died
14 (2.5%)
Gender Distribution
Female 306 (49.8%)
Male 297 (48.3%)
Unknown 9 (1.5%)
Mixed 3 (0.5%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 18 | |
| 2011 | 34 | |
| 2012 | 47 | |
| 2013 | 42 | |
| 2014 | 54 | |
| 2015 | 51 | |
| 2016 | 46 | |
| 2017 | 45 | |
| 2018 | 47 | |
| 2019 | 41 | |
| 2020 | 29 | |
| 2021 | 23 | |
| 2022 | 45 | |
| 2023 | 37 | |
| 2024 | 32 | |
| 2025 | 24 | |
Griffon - Brussels Pet Health Insights
Griffon - Brussels accounts for 615 FDA adverse event reports, ranking #128 by volume among dog breeds, with 31 reports (5.0%) coded as a death outcome. Mean age at report: 6.7 years, average weight 7.1 kg (15.7 lbs).
Top reported signs: Vomiting (158), Lethargy (see also Central nervous system depression in 'Neurological') (60), Diarrhoea (55). Most-referenced drug: Milbemycin Oxime + Spinosad (102 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (48) and Afoxolaner (37).
Outcome coding on 571 status-recorded reports is dominated by Recovered/Normal (37.0%). Annual submissions ranged 2,010-2,025 across 16 years on file.
Dog Breeds With a Similar Report Volume
Dachshund - Standard Smooth-haired
621 reports · 8.2% death rate
Setter - Irish Red
640 reports · 3.9% death rate
Coonhound - Black and Tan
654 reports · 3.1% death rate
Sheepdog - Old English
569 reports · 4.0% death rate
Black Mouth Cur
564 reports · 2.0% death rate
Corso Dog
564 reports · 4.3% death rate
Frequently Asked Questions
How many FDA adverse event reports involve Griffon - Brussels? ▼
There are 615 adverse event reports involving Griffon - Brussels in the FDA database, with 31 reports involving death (5.0% death rate). Griffon - Brussels ranks #128 by report volume.
What are the most common adverse reactions reported for Griffon - Brussels? ▼
The most commonly reported adverse reactions for Griffon - Brussels are Vomiting (158 reports), Lethargy (see also Central nervous system depression in 'Neurological') (60 reports), Diarrhoea (55 reports), Emesis (54 reports), Lack of efficacy - NOS (42 reports).
What drugs are most frequently associated with Griffon - Brussels adverse events? ▼
The drugs most frequently referenced in Griffon - Brussels adverse event reports are Milbemycin Oxime + Spinosad (102 reports), Ivermectin + Pyrantel As Pamoate Salt (48 reports), Afoxolaner (37 reports), Spinosad (35 reports), Fluralaner Chew Tablets (34 reports).
What is the average age of Griffon - Brussels in adverse event reports? ▼
The average age of Griffon - Brussels at the time of adverse event reports is 6.7 years, with an average weight of 7.1 kg (15.7 lbs).
Does a high number of adverse event reports mean Griffon - Brussels is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Griffon - Brussels safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how death rate and rankings are computed.
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. Breed figures are computed directly from FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.