Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
10
Total Reports
3
Deaths Reported
3000.0%
Death Rate
4.3 yr
Avg Age at Report
Average weight at time of report: 18.8 kg (41.5 lbs)
Top Reported Reactions
Vomiting 3
Emesis 2
Recumbency 2
Death by euthanasia 2
Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders') 1
Circulatory shock 1
Unresponsive to stimuli 1
Disseminated intravascular coagulation 1
Hypoglycaemia 1
Vascular disorder NOS (see also endocarditis) 1
Bloody diarrhoea 1
Lethargy (see also Central nervous system depression in 'Neurological') 1
Lack of efficacy (bacteria) - NOS 1
Lack of efficacy (tick) 1
Lack of efficacy (protozoa) - Ehrlichia 1
Most Referenced Drugs
Milbemycin Oxime + Spinosad 3
Ivermectin, Pyrantel 1
Capromorelin Tartrate 1
Afoxolaner 1
Sarolaner 1
Pyrantel Pamoate;Sarolaner 1
Recombinant E. Coli Bl21;Recombinant E. Coli Ecl19 1
Grapiprant 1
Gentamicin + Mometasone + Clotrimazole 1
Oclacitinib Maleate 1
Anti-Il31 Mab Mcs Lot #1283563 1
Fluoxetine Hydrochloride 1
Outcome Breakdown
Recovered/Normal
3 (30.0%)
Died
2 (20.0%)
Outcome Unknown
2 (20.0%)
Ongoing
2 (20.0%)
Euthanized
1 (10.0%)
Gender Distribution
Female 8 (80.0%)
Male 2 (20.0%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2013 | 1 | |
| 2015 | 1 | |
| 2016 | 2 | |
| 2020 | 2 | |
| 2021 | 2 | |
| 2024 | 1 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #435 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.