Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
7
Total Reports
1
Deaths Reported
1430.0%
Death Rate
6.1 yr
Avg Age at Report
Average weight at time of report: 26.4 kg (58.2 lbs)
Top Reported Reactions
Behavioural disorder NOS 2
Lethargy (see also Central nervous system depression in 'Neurological') 1
Not eating 1
Lack of efficacy - NOS 1
Lack of efficacy (endoparasite) - heartworm 1
Stroke 1
Death 1
Collapse NOS (see also Cardio-vascular and Neurological disorders) 1
Vomiting 1
Lethargy (see also Central nervous system depression in Neurological) 1
Most Referenced Drugs
Grapiprant 3
Milbemycin Oxime + Praziquantel 2
Lotilaner 2
Milbemycin Oxime + Spinosad 2
Fluoxetine 1
Avocado/Soybean Unsaponifiable + Glucosamine + Sodium Chondroitin Sulfate 1
Herbal Supplement 1
Stem Cell Therapy 1
Ivermectin 1
Gabapentin 1
Outcome Breakdown
Ongoing
2 (28.6%)
Outcome Unknown
2 (28.6%)
Recovered/Normal
2 (28.6%)
Died
1 (14.3%)
Gender Distribution
Male 4 (57.1%)
Female 3 (42.9%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2017 | 1 | |
| 2020 | 1 | |
| 2021 | 2 | |
| 2024 | 1 | |
| 2025 | 2 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #469 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.