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Breed profile · FDA CVM July 2026 extract

American Curl Longhair adverse-event record

Adverse-event filings for American Curl Longhair (Cat) in the FDA Center for Veterinary Medicine openFDA extract. Browse cat breeds, reactions, and outcomes below.

#400 of 510
by report volume (all breeds)
15
FDA CVM reports on file
6.7%
death-coded share of reports
3
Vomiting - top reaction

How the 15 reports break down

By recorded gender -- every report on file for American Curl Longhair, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 4 3 2 1 0 2015 2019 2020 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for American Curl Longhair drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, American Curl Longhair ranks #400 of 510 by total reports (15). Death-coded-share rank requires at least 50 reports. National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#400
This breed, reports of 510

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. American Curl Longhair has 15 reports now versus 14 in that prior snapshot: 1 more (7.1%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to American Curl Longhair changes

Total Reports

15

Low report volume

Deaths Reported

1

of 15 reports

Death-coded share of reports

6.7%

6.7% death-coded

Avg Age at Report

8.0 yr

4.9 kg avg weight

Death-Coded Outcome Share

American Curl Longhair death-coded reports 6.7%
Cross-breed median

6.7% of 15 american curl longhair reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 4.9 kg (10.8 lbs)

Top Reported Reactions

Vomiting 3
Diarrhoea 2
Ataxia 2
Hyperproteinaemia 2
Decreased packed cell volume (PCV) 2

Most Referenced Drugs

Fluralaner Spot-On Solution 3
Frunevetmab 2
Selamectin;Sarolaner 2
Velagliflozin Proline Monohydrate 2
Cyclosporine A 1

Outcome Breakdown

Ongoing
8 (53.3%)
Outcome Unknown
6 (40.0%)
Euthanized
1 (6.7%)

Gender Distribution

Male 8 (53.3%)
Female 7 (46.7%)

Reports by Year

Year Reports Trend
2013 1
2015 1
2019 1
2020 1
2022 1
2023 4
2024 3
2025 2
2026 1

American Curl Longhair: high death-coded share in the FDA CVM extract

Signature read: 15 reports place American Curl Longhair in the lower third of breed filing volume (#400 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, American Curl Longhair sits at #400 of 510 by report volume among all breeds and #45 of 55 among cat breeds, with 15 reports and 1 (6.7%) death-coded. Mean age at report: 8.0 years, average weight 4.9 kg (10.8 lbs).

Top reported signs: Vomiting (3), Diarrhoea (2), Ataxia (2). Most-referenced drug: Fluralaner Spot-On Solution (3 reports), followed by Frunevetmab (2) and Selamectin;Sarolaner (2).

Outcome coding on 15 status-recorded reports is dominated by Ongoing (53.3%). Annual submissions ranged 1-2,026 across 9 years on file.

Cat Breeds With a Similar Report Volume

Showing 6 of 54 cat breeds in our dataset, ranked by closest report volume.

Nationwide breeds with similar profiles

Sparse-volume peer sets for American Curl Longhair drawn from openFDA outside the Cat family so the neighborhoods are not species containment (the similar-volume list above stays within species).

What to do with this cat

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve American Curl Longhair?
There are 15 adverse event reports involving American Curl Longhair in the FDA database, of which 1 were death-coded (6.7% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, American Curl Longhair ranks #400 of 510 by report volume among all breeds PlainBreed indexes (#45 of 55 among cat breeds).
Where does American Curl Longhair sit among other breeds in PlainBreed's corpus?
According to FDA CVM report volume, American Curl Longhair is #400 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Cat, it is #45 of 55. It has fewer than 50 reports, so it is outside the death-rate ranking cohort (≥50 reports). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for American Curl Longhair?
The most commonly reported adverse reactions for American Curl Longhair are Vomiting (3 reports), Diarrhoea (2 reports), Ataxia (2 reports), Hyperproteinaemia (2 reports), Decreased packed cell volume (PCV) (2 reports).
What drugs are most frequently associated with American Curl Longhair adverse events?
The drugs most frequently referenced in American Curl Longhair adverse event reports are Fluralaner Spot-On Solution (3 reports), Frunevetmab (2 reports), Selamectin;Sarolaner (2 reports), Velagliflozin Proline Monohydrate (2 reports), Cyclosporine A (1 reports).
What is the average age of American Curl Longhair in adverse event reports?
The average age of American Curl Longhair at the time of adverse event reports is 8.0 years, with an average weight of 4.9 kg (10.8 lbs).

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for American Curl Longhair (Cat), extract as of July 2026 extract. 15 reports · 1 death-coded (6.7% of reports, not a mortality rate) · #400 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →