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Breed profile · FDA CVM July 2026 extract

Alaskan Malamute adverse-event record

Adverse-event filings for Alaskan Malamute (Dog) in the FDA Center for Veterinary Medicine openFDA extract. Browse dog breeds, reactions, and outcomes below.

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#115 of 510
by report volume (all breeds)
868
FDA CVM reports on file
5.1%
death-coded share of reports
#127 of 275
by death-coded share (≥50 reports)

How the 868 reports break down

By recorded gender -- every report on file for Alaskan Malamute, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 64 48 32 16 0 2019 2020 2021 2022 2023 2024 2025 2026 Reports filed Death-coded reports
Annual report volume for Alaskan Malamute drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Alaskan Malamute ranks #115 of 510 by total reports (868) and #127 of 275 by death-coded share (5.1%). National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#115
This breed, reports of 510
#127
This breed, death share of 275

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Alaskan Malamute has 868 reports now versus 851 in that prior snapshot: 17 more (2.0%).

Report change
+17
Death-coded reports
+2
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Alaskan Malamute changes

Total Reports

868

High report volume

Deaths Reported

44

of 868 reports

Death-coded share of reports

5.1%

Above-median death-coded share

Avg Age at Report

5.4 yr

38.3 kg avg weight

Breed Safety Scorecard

D (43/100)

A weighted composite across 4 of 4 dimensions, each benchmarked against every tracked breed with at least 200 reports (n=185). Dimensions with insufficient data drop out and their weight redistributes to the rest, so a missing input never silently deflates the score.

Death rate D
5.1%

Share of reports coded as a fatality

Euthanasia rate C
2.0%

Share of reports resulting in euthanasia

Full recovery rate D
27.3%

Share of reports coded "Recovered/Normal"

5-year trend F
+37%

Change in annual report volume over the last 5 complete years

Death-Coded Outcome Share

Alaskan Malamute death-coded reports 5.1%
Cross-breed median

5.1% of 868 alaskan malamute reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Where Alaskan Malamute's death-coded share sits among indexed breeds

Death-coded share of FDA CVM reports, breeds with ≥50 reports (July 2026 extract)

5% 53rd percentile Higher share than 53% of 275 indexed breeds

5%–10%: 1 indexed breeds (0%). This entry sits in this band. 20%–25%: 2 indexed breeds (1%). Above this entry. 25%–30%: 3 indexed breeds (1%). Above this entry. 30%–35%: 4 indexed breeds (1%). Above this entry. 35%–40%: 5 indexed breeds (2%). Above this entry. 40%–45%: 6 indexed breeds (2%). Above this entry. 45%–50%: 3 indexed breeds (1%). Above this entry. 50%–55%: 7 indexed breeds (3%). Above this entry. 55%–60%: 7 indexed breeds (3%). Above this entry. 60%–65%: 21 indexed breeds (8%). Above this entry. 65%–70%: 11 indexed breeds (4%). Above this entry. 70%–75%: 15 indexed breeds (5%). Above this entry. 75%–80%: 13 indexed breeds (5%). Above this entry. 80%–85%: 11 indexed breeds (4%). Above this entry. 85%–90%: 12 indexed breeds (4%). Above this entry. 90%–95%: 12 indexed breeds (4%). Above this entry. 95%–100%: 142 indexed breeds (52%). Above this entry. Alaskan Malamute 5% 100% every breed with ≥50 FDA reports, bucketed by value

Each bar is a band; taller bars hold more indexed breeds. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source FDA Center for Veterinary Medicine, openFDA adverse event extract (PlainBreed) · July 2026 extract

This histogram uses the same ≥50-report cohort as the highest death-coded share ranking. A higher share means more of this breed's reported events were death-coded, not a mortality rate for living animals.

Average weight at time of report: 38.3 kg (84.5 lbs)

Top Reported Reactions

Vomiting 154
Lethargy (see also Central nervous system depression in 'Neurological') 99
Diarrhoea 82
Emesis 54
Lack of efficacy - NOS 53
Lack of efficacy (endoparasite) - heartworm 51
Lack of efficacy (endoparasite) - hookworm 46
INEFFECTIVE, HEARTWORM LARVAE 41

Most Referenced Drugs

Milbemycin Oxime + Spinosad 150
Ivermectin + Pyrantel As Pamoate Salt 96
Pyrantel Pamoate;Sarolaner 70
Afoxolaner 62
Bedinvetmab 48
Milbemycin Oxime + Praziquantel 47
Spinosad 32
Fluralaner Chew Tablets 31

Outcome Breakdown

Outcome Unknown
272 (33.4%)
Recovered/Normal
237 (29.1%)
Ongoing
226 (27.7%)
Recovered with Sequela
36 (4.4%)
Died
27 (3.3%)
Euthanized
17 (2.1%)

Gender Distribution

Male 457 (52.6%)
Female 394 (45.4%)
Unknown 12 (1.4%)
Mixed 5 (0.6%)

Reports by Year

Year Reports Trend
2010 23
2011 33
2012 57
2013 59
2014 49
2015 67
2016 61
2017 67
2018 57
2019 64
2020 54
2021 46
2022 46
2023 53
2024 56
2025 63
2026 13

Alaskan Malamute: high-volume FDA adverse-event cohort

Signature read: 868 reports place Alaskan Malamute in the upper third of breed filing volume (#115 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Alaskan Malamute sits at #115 of 510 by report volume among all breeds and #96 of 298 among dog breeds, with 868 reports and 44 (5.1%) death-coded. On death-coded share among breeds with ≥50 reports, it ranks #127 of 275. Mean age at report: 5.4 years, average weight 38.3 kg (84.5 lbs).

Top reported signs: Vomiting (154), Lethargy (see also Central nervous system depression in 'Neurological') (99), Diarrhoea (82). Most-referenced drug: Milbemycin Oxime + Spinosad (150 reports), followed by Ivermectin + Pyrantel As Pamoate Salt (96) and Pyrantel Pamoate;Sarolaner (70).

Outcome coding on 815 status-recorded reports is dominated by Outcome Unknown (33.4%). Annual submissions ranged 13-2,026 across 17 years on file.

Dog Breeds With a Similar Report Volume

Showing 6 of 297 dog breeds in our dataset, ranked by closest report volume.

Terrier - Fox (unspecified)
860 reports · 4.7% death-coded
Terrier - Airedale
893 reports · 6.2% death-coded
Greyhound - Italian
836 reports · 2.8% death-coded
Coton de Tuléar
780 reports · 3.1% death-coded
Spaniel - Springer (unspecified)
983 reports · 5.2% death-coded
Whippet
749 reports · 5.1% death-coded

Nationwide breeds with similar profiles

High-volume peer sets for Alaskan Malamute drawn from openFDA outside the Dog family so the neighborhoods are not species containment (the similar-volume list above stays within species).

Similar death-coded share

Nearest other-species breeds with ≥50 reports (5.1% death-coded here).

Egyptian Mau 5.3% · Cat Scottish Fold Longhair 4.8% · Cat Bengal 4.6% · Cat Norwegian Forest 5.7% · Cat

What to do with this dog

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Alaskan Malamute? ▼
There are 868 adverse event reports involving Alaskan Malamute in the FDA database, of which 44 were death-coded (5.1% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Alaskan Malamute ranks #115 of 510 by report volume among all breeds PlainBreed indexes (#96 of 298 among dog breeds).
Where does Alaskan Malamute sit among other breeds in PlainBreed's corpus? ▼
According to FDA CVM report volume, Alaskan Malamute is #115 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Dog, it is #96 of 298. Among breeds with at least 50 reports, its death-coded share ranks #127 of 275 (same cohort as highest-death-rate). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Alaskan Malamute? ▼
The most commonly reported adverse reactions for Alaskan Malamute are Vomiting (154 reports), Lethargy (see also Central nervous system depression in 'Neurological') (99 reports), Diarrhoea (82 reports), Emesis (54 reports), Lack of efficacy - NOS (53 reports).
What drugs are most frequently associated with Alaskan Malamute adverse events? ▼
The drugs most frequently referenced in Alaskan Malamute adverse event reports are Milbemycin Oxime + Spinosad (150 reports), Ivermectin + Pyrantel As Pamoate Salt (96 reports), Pyrantel Pamoate;Sarolaner (70 reports), Afoxolaner (62 reports), Bedinvetmab (48 reports).
What is the average age of Alaskan Malamute in adverse event reports? ▼
The average age of Alaskan Malamute at the time of adverse event reports is 5.4 years, with an average weight of 38.3 kg (84.5 lbs).

Compare a breed's report volume against how common the breed is before drawing conclusions. See our methodology for how the death-coded share and rankings are computed, or read breed-specific reporting patterns and FDA CVM reporting.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Alaskan Malamute (Dog), extract as of July 2026 extract. 868 reports · 44 death-coded (5.1% of reports, not a mortality rate) · #115 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →