Drug profile

The FDA adverse-event record for Velagliflozin

43 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Velagliflozin. See the species affected, top reactions, and outcomes below.

43
adverse-event reports
9.3%
death-coded share
Cat
most-reported species
12
Ketosis - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
43
Total Reports
4
Deaths Reported
9.3%
Death Rate

Active Ingredients

Velagliflozin

Administration Routes

UnknownOral

Species Affected

Cat 42
Unknown 1

Most Affected Breeds

Domestic Shorthair 29
Cat (unknown) 5
Domestic Longhair 4
Domestic Mediumhair 1
Siamese 1
Russian 1
Turkish Van 1
Unknown 1

Most Reported Reactions

Ketosis 12
Lack of efficacy - NOS 12
Diarrhoea 10
Weight loss 7
Glucosuria 7
Hyperglycaemia 6
Vomiting 6
Elevated symmetrical dimethylarginine (SDMA) 6
Elevated blood urea nitrogen (BUN) 5
Elevated creatinine 5
Other abnormal test result NOS 4
Death by euthanasia 4

Outcome Breakdown

Outcome Unknown
20 (47.6%)
Ongoing
13 (31.0%)
Recovered/Normal
5 (11.9%)
Euthanized
4 (9.5%)

Velagliflozin Adverse Event Insights

43 reports name Velagliflozin; 4 recorded a death outcome (9.3% of reported events, not a population-level mortality rate). Active ingredient: Velagliflozin. Administration routes: Unknown, Oral.

By species: Cat (42 reports), Unknown (1 reports). By breed: Domestic Shorthair (29), Cat (unknown) (5), Domestic Longhair (4).

Leading clinical signs: Ketosis (12), Lack of efficacy - NOS (12), Diarrhoea (10), Weight loss (7). Outcome, 42 coded reports: Outcome Unknown leads at 47.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.