Lysozyme & Lactoferrin

Verify with FDA CVM →

54 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
54
Total Reports
8
Deaths Reported
1480.0%
Death Rate

Active Ingredients

Lysozyme & Lactoferrin

Administration Routes

UnknownAuricular (Otic)Topical

Species Affected

Dog 52
Cat 2

Most Affected Breeds

Retriever - Labrador 10
Spaniel (unspecified) 4
Terrier - Yorkshire 4
Shih Tzu 2
Domestic Shorthair 2
Beagle 2
Shepherd Dog - German 2
Chihuahua 2
Pug 2
Bichon Frise 2

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 11
Vomiting 7
Behavioural disorder NOS 6
Anorexia 6
Other abnormal test result NOS 5
Panting 5
Death by euthanasia 5
Abnormal ultrasound finding 4
Diarrhoea 4
Facial swelling (see also 'Skin') 4
Anaphylactoid reaction 4
INEFFECTIVE, LOSS OF EFFECT 4

Outcome Breakdown

Ongoing
27 (50.0%)
Recovered/Normal
15 (27.8%)
Euthanized
5 (9.3%)
Outcome Unknown
4 (7.4%)
Died
3 (5.6%)

Data Summary

Metric Value
Total adverse event reports 54
Reports involving death 8
Case-fatality rate (reported events) 1480.0%
Distinct species in reports 2
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Lysozyme & Lactoferrin Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 54 adverse event reports referencing Lysozyme & Lactoferrin, including 8 reports in which the animal died — a 1480.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Lysozyme & Lactoferrin. Reported administration routes include Unknown, Auricular (Otic), Topical. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Lysozyme & Lactoferrin reports are Dog (52 reports), Cat (2 reports), with Dog accounting for the largest share. Within those species, Retriever - Labrador (10), Spaniel (unspecified) (4), Terrier - Yorkshire (4) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Lysozyme & Lactoferrin are Lethargy (see also Central nervous system depression in 'Neurological') (11), Vomiting (7), Behavioural disorder NOS (6), Anorexia (6). Of the 54 reports with a coded outcome, Ongoing is the leading category at 50.0%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Lysozyme & Lactoferrin.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial