Unspecified Vaccines

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226 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
226
Total Reports
21
Deaths Reported
930.0%
Death Rate

Active Ingredients

Unspecified Vaccines

Administration Routes

UnknownSubcutaneousTopical

Species Affected

Dog 176
Cat 49
Cattle 1

Most Affected Breeds

Domestic Shorthair 34
Retriever - Labrador 29
Retriever - Golden 13
Chihuahua 8
Shih Tzu 8
Crossbred Canine/dog 8
Shepherd Dog - German 7
Dog (unknown) 6
Terrier - Yorkshire 5
Dachshund (unspecified) 5

Most Reported Reactions

Vomiting 58
Diarrhoea 38
Lethargy (see also Central nervous system depression in 'Neurological') 25
Seizure NOS 18
Anorexia 17
Lethargy (see also Central nervous system depression in Neurological) 16
Decreased appetite 14
Emesis (multiple) 13
Death by euthanasia 12
Weight loss 11
Fever 11
Behavioural disorder NOS 11

Outcome Breakdown

Outcome Unknown
79 (35.0%)
Recovered/Normal
74 (32.7%)
Ongoing
51 (22.6%)
Euthanized
12 (5.3%)
Died
9 (4.0%)
Recovered with Sequela
1 (0.4%)

Data Summary

Metric Value
Total adverse event reports 226
Reports involving death 21
Case-fatality rate (reported events) 930.0%
Distinct species in reports 3
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Unspecified Vaccines Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 226 adverse event reports referencing Unspecified Vaccines, including 21 reports in which the animal died — a 930.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Unspecified Vaccines. Reported administration routes include Unknown, Subcutaneous, Topical. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Unspecified Vaccines reports are Dog (176 reports), Cat (49 reports), Cattle (1 reports), with Dog accounting for the largest share. Within those species, Domestic Shorthair (34), Retriever - Labrador (29), Retriever - Golden (13) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Unspecified Vaccines are Vomiting (58), Diarrhoea (38), Lethargy (see also Central nervous system depression in 'Neurological') (25), Seizure NOS (18). Of the 226 reports with a coded outcome, Outcome Unknown is the leading category at 35.0%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Unspecified Vaccines.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial