Bupivacaine
614 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
614
Total Reports
54
Deaths Reported
880.0%
Death Rate
Active Ingredients
Bupivacaine
Administration Routes
UnknownParenteralOtherSubcutaneousOralEpiduralIntraocularTopicalPerineuralIntradermal
Species Affected
Dog 222
Cat 219
Unknown 154
Human 12
Rabbit 2
Pig 2
Horse 1
Rat 1
Cephalopoda 1
Most Affected Breeds
Unknown 169
Domestic Shorthair 123
Dog (unknown) 56
Retriever - Labrador 33
Cat (unknown) 23
Domestic Longhair 22
Domestic Mediumhair 18
Retriever - Golden 14
Boxer (German Boxer) 10
Crossbred Canine/dog 7
Most Reported Reactions
Not eating 48
Vials, Damaged 37
Decreased appetite 32
Behavioural disorder NOS 31
Other abnormal test result NOS 30
Death 28
Vomiting 25
Bruising 25
Death by euthanasia 24
Dilated pupils 24
Anorexia 23
Lethargy (see also Central nervous system depression in 'Neurological') 23
Outcome Breakdown
Recovered/Normal
152 (32.8%)
Ongoing
128 (27.6%)
Outcome Unknown
124 (26.8%)
Died
31 (6.7%)
Euthanized
25 (5.4%)
Recovered with Sequela
3 (0.6%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.