Drug profile
The FDA adverse-event record for Trenbolone Acetate;Estradiol Benzoate
212 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Trenbolone Acetate;Estradiol Benzoate. See the species affected, top reactions, and outcomes below.
- 212
- adverse-event reports
- 25.9%
- death-coded share
- Cattle
- most-reported species
- 70
- Increased sexual interest - top reaction
Active Ingredients
Administration Routes
Species Affected
Most Affected Breeds
Most Reported Reactions
Outcome Breakdown
Trenbolone Acetate;Estradiol Benzoate Adverse Event Insights
212 reports name Trenbolone Acetate;Estradiol Benzoate; 55 recorded a death outcome (25.9% of reported events, not a population-level mortality rate). Active ingredient: Trenbolone Acetate;Estradiol Benzoate. Administration routes: Unknown, Subcutaneous.
By species: Cattle (170 reports), Unknown (40 reports), Human (2 reports). By breed: Mixed (Cattle) (129), Unknown (42), Holstein-Friesian also known as Holstein (26).
Leading clinical signs: Increased sexual interest (70), Death (38), Sexual disorder NOS (see 'Reproductive' for named sexual disorders) (28), Implant, Abnormal (18). Outcome, 218 coded reports: Outcome Unknown leads at 55.5%.
Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.
Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.