Neomycin Sulfate;Tetracaine Hydrochloride

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93 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
93
Total Reports
10
Deaths Reported
1080.0%
Death Rate

Active Ingredients

Neomycin Sulfate;Tetracaine Hydrochloride

Administration Routes

TopicalUnknownOphthalmicOralOtherRespiratory (Inhalation)Intraocular

Species Affected

Dog 68
Unknown 11
Cat 7
Human 6
Cattle 1

Most Affected Breeds

Unknown 17
Retriever - Labrador 9
Retriever - Golden 4
Maltese 4
Dog (unknown) 3
Shepherd Dog - German 3
Siberian Husky 3
Terrier - Bull - American Pit 3
Bichon Frise 2
Domestic Mediumhair 2

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 12
Polydipsia 12
Lack of efficacy - NOS 11
Polyuria 9
Diarrhoea 9
Vomiting 9
Death by euthanasia 8
Anorexia 7
Seizure NOS 7
Lethargy (see also Central nervous system depression in Neurological) 7
Loose stool 6
Urinary incontinence 6

Outcome Breakdown

Ongoing
36 (43.9%)
Outcome Unknown
24 (29.3%)
Recovered/Normal
12 (14.6%)
Euthanized
8 (9.8%)
Died
2 (2.4%)

Data Summary

Metric Value
Total adverse event reports 93
Reports involving death 10
Case-fatality rate (reported events) 1080.0%
Distinct species in reports 5
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Neomycin Sulfate;Tetracaine Hydrochloride Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 93 adverse event reports referencing Neomycin Sulfate;Tetracaine Hydrochloride, including 10 reports in which the animal died — a 1080.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Neomycin Sulfate;Tetracaine Hydrochloride. Reported administration routes include Topical, Unknown, Ophthalmic, Oral. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Neomycin Sulfate;Tetracaine Hydrochloride reports are Dog (68 reports), Unknown (11 reports), Cat (7 reports), with Dog accounting for the largest share. Within those species, Unknown (17), Retriever - Labrador (9), Retriever - Golden (4) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Neomycin Sulfate;Tetracaine Hydrochloride are Lethargy (see also Central nervous system depression in 'Neurological') (12), Polydipsia (12), Lack of efficacy - NOS (11), Polyuria (9). Of the 82 reports with a coded outcome, Ongoing is the leading category at 43.9%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Neomycin Sulfate;Tetracaine Hydrochloride.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial