Drug profile

The FDA adverse-event record for Unspecified Flea Shampoo

127 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Unspecified Flea Shampoo. See the species affected, top reactions, and outcomes below.

127
adverse-event reports
0.8%
death-coded share
Dog
most-reported species
106
Lack of efficacy (ectoparasite) - flea - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
127
Total Reports
1
Deaths Reported
0.8%
Death Rate

Active Ingredients

Unspecified Flea Shampoo

Administration Routes

TopicalUnknown

Species Affected

Dog 107
Cat 19
Other 1

Most Affected Breeds

Chihuahua 13
Domestic Shorthair 12
Terrier - Yorkshire 11
Cat (unknown) 6
Shepherd Dog - Australian 5
Retriever - Labrador 5
Dog (unknown) 5
Maltese 5
Spitz - German Pomeranian 5
Shih Tzu 4

Most Reported Reactions

Lack of efficacy (ectoparasite) - flea 106
Pruritus 14
Behavioural disorder NOS 5
Panting 5
Restlessness 4
Itching 4
Scratching 3
Hypersalivation 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Rolling 2
Skin lesion NOS 2
Whining 2

Outcome Breakdown

Outcome Unknown
112 (88.2%)
Recovered/Normal
8 (6.3%)
Ongoing
6 (4.7%)
Euthanized
1 (0.8%)

Unspecified Flea Shampoo Adverse Event Insights

127 reports name Unspecified Flea Shampoo; 1 recorded a death outcome (0.8% of reported events, not a population-level mortality rate). Active ingredient: Unspecified Flea Shampoo. Administration routes: Topical, Unknown.

By species: Dog (107 reports), Cat (19 reports), Other (1 reports). By breed: Chihuahua (13), Domestic Shorthair (12), Terrier - Yorkshire (11).

Leading clinical signs: Lack of efficacy (ectoparasite) - flea (106), Pruritus (14), Behavioural disorder NOS (5), Panting (5). Outcome, 127 coded reports: Outcome Unknown leads at 88.2%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.