Drug profile

The FDA adverse-event record for Glucosamine Supplement

128 FDA reports name Glucosamine Supplement, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#685 of 2,679
by report volume (all drugs)
128
adverse-event reports
13.3%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Glucosamine Supplement ranks #685 of 2679 by total reports (128) and #417 of 1130 by death-coded share (13.3%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#685
This drug, reports of 2679
#417
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Glucosamine Supplement has 128 reports now versus 117 in that prior snapshot: 11 more (9.4%).

Report change
+11
Death-coded reports
+0
Death-coded share
−1.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Glucosamine Supplement changes

Signature read: death-coded report count at 17 is the most distinctive stamp on Glucosamine Supplement's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
128
Total Reports
17
Deaths Reported
13.3%
Death-coded share of reports

Active Ingredients

Glucosamine Supplement

Administration Routes

OralUnknown

Species Affected

Dog 124
Cat 4

Most Affected Breeds

Retriever - Labrador 30
Shepherd Dog - German 17
Retriever - Golden 10
Dog (other) 4
Shepherd Dog - Australian 4
Boxer (German Boxer) 3
Sheepdog - Shetland 3
Domestic Shorthair 3
Chihuahua 3
Terrier - Bull - American Pit 2

Most Reported Reactions

Other abnormal test result NOS 26
Vomiting 20
Lethargy (see also Central nervous system depression in 'Neurological') 19
Diarrhoea 14
Abnormal radiograph finding 13
Decreased appetite 11
Death by euthanasia 11
Weight loss 10
Emesis (multiple) 9
Anaemia NOS 9
Lack of efficacy - NOS 9
Anorexia 8

Outcome Breakdown

Ongoing
54 (42.2%)
Recovered/Normal
32 (25.0%)
Outcome Unknown
24 (18.8%)
Euthanized
11 (8.6%)
Died
6 (4.7%)
Recovered with Sequela
1 (0.8%)

Glucosamine Supplement: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Glucosamine Supplement, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Glucosamine Supplement's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Glucosamine Supplement (#685 of 2,679 by report volume); death-coded 13.3%. PlainBreed drug row · death-coded report count stamp 17 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →