Drug profile

The FDA adverse-event record for Same

87 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Same. See the species affected, top reactions, and outcomes below.

87
adverse-event reports
21.8%
death-coded share
Dog
most-reported species
24
Elevated alanine aminotransferase (ALT) - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
87
Total Reports
19
Deaths Reported
21.8%
Death Rate

Active Ingredients

Same

Administration Routes

OralUnknown

Species Affected

Dog 82
Cat 5

Most Affected Breeds

Beagle 7
Terrier - Yorkshire 6
Dachshund - Standard Long-haired 5
Domestic Shorthair 5
Crossbred Canine/dog 4
Schnauzer - Miniature 4
Shih Tzu 4
Retriever - Labrador 4
Chihuahua 3
Schnauzer (unspecified) 3

Most Reported Reactions

Elevated alanine aminotransferase (ALT) 24
Vomiting 17
Elevated serum alkaline phosphatase (SAP) 15
Diarrhoea 14
Lethargy (see also Central nervous system depression in 'Neurological') 12
Elevated blood urea nitrogen (BUN) 11
Death 10
Underdose 10
Death by euthanasia 9
Seizure NOS 9
Anorexia 7
Hyperkalaemia 7

Outcome Breakdown

Outcome Unknown
32 (36.8%)
Recovered/Normal
19 (21.8%)
Ongoing
14 (16.1%)
Died
10 (11.5%)
Euthanized
9 (10.3%)
Recovered with Sequela
3 (3.4%)

Same Adverse Event Insights

87 reports name Same; 19 recorded a death outcome (21.8% of reported events, not a population-level mortality rate). Active ingredient: Same. Administration routes: Oral, Unknown.

By species: Dog (82 reports), Cat (5 reports). By breed: Beagle (7), Terrier - Yorkshire (6), Dachshund - Standard Long-haired (5).

Leading clinical signs: Elevated alanine aminotransferase (ALT) (24), Vomiting (17), Elevated serum alkaline phosphatase (SAP) (15), Diarrhoea (14). Outcome, 87 coded reports: Outcome Unknown leads at 36.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.