Heartworm Prevention
90 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
90
Total Reports
7
Deaths Reported
780.0%
Death Rate
Active Ingredients
Heartworm Prevention
Administration Routes
UnknownOralSubcutaneousTopical
Species Affected
Dog 90
Most Affected Breeds
Retriever - Labrador 11
Crossbred Canine/dog 6
Retriever - Golden 5
Bichon Frise 5
Beagle 4
Lhasa Apso 3
Dog (unknown) 3
Spitz - German Pomeranian 3
Terrier (unspecified) 3
Spaniel - Springer English 2
Most Reported Reactions
Vomiting 23
Lethargy (see also Central nervous system depression in 'Neurological') 16
Lack of efficacy - NOS 13
INEFFECTIVE, LOSS OF EFFECT 9
Other abnormal test result NOS 8
Lack of efficacy (endoparasite) - heartworm 8
Anorexia 6
Elevated alanine aminotransferase (ALT) 6
Death by euthanasia 6
Diarrhoea 5
Panting 5
Abnormal radiograph finding 5
Outcome Breakdown
Ongoing
38 (42.2%)
Recovered/Normal
24 (26.7%)
Outcome Unknown
21 (23.3%)
Euthanized
6 (6.7%)
Died
1 (1.1%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.