Drug profile

The FDA adverse-event record for Deramaxx

93 FDA reports name Deramaxx, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#807 of 2,679
by report volume (all drugs)
93
adverse-event reports
32.3%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Deramaxx ranks #806 of 2679 by total reports (93) and #111 of 1130 by death-coded share (32.3%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#806
This drug, reports of 2679
#111
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Deramaxx has 93 reports now versus 93 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Deramaxx changes

Signature read: Deramaxx's 32.3% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
93
Total Reports
30
Deaths Reported
32.3%
Death-coded share of reports

Active Ingredients

Deramaxx

Administration Routes

OralUnknown

Species Affected

Dog 93

Most Affected Breeds

Retriever - Labrador 17
Terrier - Bull - American Pit 8
Retriever - Golden 8
Crossbred Canine/dog 5
Collie - Border 3
Shepherd Dog - German 3
Beagle 3
Chow Chow 2
Terrier (unspecified) 2
Deutsche Dogge, Great Dane 2

Most Reported Reactions

Death by euthanasia 25
Vomiting 16
Seizure NOS 14
Lethargy (see also Central nervous system depression in Neurological) 14
Diarrhoea 13
Ataxia 12
Polydipsia 8
Polyuria 7
Weakness 7
Elevated alanine aminotransferase (ALT) 7
Urinary incontinence 7
Limb weakness 7

Outcome Breakdown

Ongoing
36 (38.7%)
Euthanized
25 (26.9%)
Outcome Unknown
14 (15.1%)
Recovered/Normal
13 (14.0%)
Died
5 (5.4%)

Deramaxx: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Deramaxx, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (32.3% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Deramaxx (#807 of 2,679 by report volume); death-coded 32.3%. PlainBreed drug row · death-coded share stamp 32.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →