Drug profile

The FDA adverse-event record for Prednisolone, Trimeprazine Tartrate

78 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Prednisolone, Trimeprazine Tartrate. See the species affected, top reactions, and outcomes below.

78
adverse-event reports
12.8%
death-coded share
Dog
most-reported species
17
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
78
Total Reports
10
Deaths Reported
12.8%
Death Rate

Active Ingredients

Prednisolone, Trimeprazine Tartrate

Administration Routes

OralUnknown

Species Affected

Dog 69
Unknown 6
Human 2
Cat 1

Most Affected Breeds

Crossbred Canine/dog 10
Unknown 8
Retriever - Labrador 7
Pug 3
Spitz - German Pomeranian 3
Terrier - Jack Russell 3
Spaniel - Cocker American 3
Chihuahua 3
Poodle (unspecified) 3
Retriever - Golden 3

Most Reported Reactions

Vomiting 17
Anorexia 12
Depression 12
Diarrhoea 10
Anaemia NOS 8
Polyuria 8
Elevated serum alkaline phosphatase (SAP) 7
Polydipsia 6
Convulsion 6
Death 5
Elevated alanine aminotransferase (ALT) 5
Bloody diarrhoea 5

Outcome Breakdown

Died
10 (100.0%)

Prednisolone, Trimeprazine Tartrate Adverse Event Insights

78 reports name Prednisolone, Trimeprazine Tartrate; 10 recorded a death outcome (12.8% of reported events, not a population-level mortality rate). Active ingredient: Prednisolone, Trimeprazine Tartrate. Administration routes: Oral, Unknown.

By species: Dog (69 reports), Unknown (6 reports), Human (2 reports). By breed: Crossbred Canine/dog (10), Unknown (8), Retriever - Labrador (7).

Leading clinical signs: Vomiting (17), Anorexia (12), Depression (12), Diarrhoea (10). Outcome, 10 coded reports: Died leads at 100.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.