Drug profile

The FDA adverse-event record for Prednisolone, Trimeprazine Tartrate

78 FDA reports name Prednisolone, Trimeprazine Tartrate, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#890 of 2,679
by report volume (all drugs)
78
adverse-event reports
12.8%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Prednisolone, Trimeprazine Tartrate ranks #884 of 2679 by total reports (78) and #427 of 1130 by death-coded share (12.8%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#884
This drug, reports of 2679
#427
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Prednisolone, Trimeprazine Tartrate has 78 reports now versus 78 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Prednisolone, Trimeprazine Tartrate changes

Signature read: death-coded report count at 10 is the most distinctive stamp on Prednisolone, Trimeprazine Tartrate's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
78
Total Reports
10
Deaths Reported
12.8%
Death-coded share of reports

Active Ingredients

Prednisolone, Trimeprazine Tartrate

Administration Routes

OralUnknown

Species Affected

Dog 69
Unknown 6
Human 2
Cat 1

Most Affected Breeds

Crossbred Canine/dog 10
Unknown 8
Retriever - Labrador 7
Pug 3
Spitz - German Pomeranian 3
Terrier - Jack Russell 3
Spaniel - Cocker American 3
Chihuahua 3
Retriever - Golden 3
Poodle (unspecified) 3

Most Reported Reactions

Vomiting 17
Anorexia 12
Depression 12
Diarrhoea 10
Anaemia NOS 8
Polyuria 8
Elevated serum alkaline phosphatase (SAP) 7
Polydipsia 6
Convulsion 6
Death 5
Elevated alanine aminotransferase (ALT) 5
Bloody diarrhoea 5

Outcome Breakdown

Died
10 (100.0%)

Prednisolone, Trimeprazine Tartrate: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Prednisolone, Trimeprazine Tartrate, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Prednisolone, Trimeprazine Tartrate's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Prednisolone, Trimeprazine Tartrate (#890 of 2,679 by report volume); death-coded 12.8%. PlainBreed drug row · death-coded report count stamp 10 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →