Drug profile

The FDA adverse-event record for Da2Ppl Vaccine

86 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Da2Ppl Vaccine. See the species affected, top reactions, and outcomes below.

86
adverse-event reports
12.8%
death-coded share
Dog
most-reported species
28
Emesis - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
86
Total Reports
11
Deaths Reported
12.8%
Death Rate

Active Ingredients

Da2Ppl Vaccine

Administration Routes

UnknownSubcutaneousParenteralOral

Species Affected

Dog 86

Most Affected Breeds

Chihuahua 8
Retriever - Labrador 8
Retriever (unspecified) 6
Maltese 4
Schnauzer (unspecified) 4
Shepherd Dog - German 3
Boxer (German Boxer) 3
Beagle 3
Terrier (unspecified) 3
Bulldog 3

Most Reported Reactions

Emesis 28
Vomiting 24
Lethargy (see also Central nervous system depression in 'Neurological') 18
Diarrhoea 9
Behavioural disorder NOS 8
Abnormal radiograph finding 7
Lack of efficacy - NOS 7
Death 6
Anorexia 6
Not eating 5
Dehydration 5
Death by euthanasia 5

Outcome Breakdown

Recovered/Normal
49 (57.0%)
Recovered with Sequela
11 (12.8%)
Outcome Unknown
9 (10.5%)
Died
7 (8.1%)
Ongoing
6 (7.0%)
Euthanized
4 (4.7%)

Da2Ppl Vaccine Adverse Event Insights

86 reports name Da2Ppl Vaccine; 11 recorded a death outcome (12.8% of reported events, not a population-level mortality rate). Active ingredient: Da2Ppl Vaccine. Administration routes: Unknown, Subcutaneous, Parenteral, Oral.

By species: Dog (86 reports). By breed: Chihuahua (8), Retriever - Labrador (8), Retriever (unspecified) (6).

Leading clinical signs: Emesis (28), Vomiting (24), Lethargy (see also Central nervous system depression in 'Neurological') (18), Diarrhoea (9). Outcome, 86 coded reports: Recovered/Normal leads at 57.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.