Methylprednisolone
276 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
276
Total Reports
37
Deaths Reported
1340.0%
Death Rate
Active Ingredients
Methylprednisolone
Administration Routes
UnknownOralParenteralSubcutaneousIntramuscularIntra-ArticularOtherEpiduralIntravenous
Species Affected
Cat 133
Dog 132
Unknown 7
Horse 4
Most Affected Breeds
Domestic Shorthair 95
Retriever - Labrador 12
Shih Tzu 10
Maltese 9
Chihuahua 8
Shepherd Dog - German 8
Domestic Longhair 8
Domestic Mediumhair 8
Unknown 7
Crossbred Canine/dog 7
Most Reported Reactions
Lethargy (see also Central nervous system depression in 'Neurological') 36
Vomiting 32
Lack of efficacy - NOS 29
Other abnormal test result NOS 25
Weight loss 22
Death by euthanasia 21
Anorexia 19
Behavioural disorder NOS 19
Death 16
Polyuria 16
Diarrhoea 16
Polydipsia 14
Outcome Breakdown
Ongoing
85 (31.7%)
Outcome Unknown
82 (30.6%)
Recovered/Normal
59 (22.0%)
Euthanized
20 (7.5%)
Died
17 (6.3%)
Recovered with Sequela
5 (1.9%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.