Drug profile

The FDA adverse-event record for Potassium Gluconate

66 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Potassium Gluconate. See the species affected, top reactions, and outcomes below.

66
adverse-event reports
22.7%
death-coded share
Cat
most-reported species
15
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
66
Total Reports
15
Deaths Reported
22.7%
Death Rate

Active Ingredients

Potassium Gluconate

Administration Routes

OralUnknownTopical

Species Affected

Cat 56
Dog 8
Unknown 2

Most Affected Breeds

Domestic Shorthair 44
Unknown 3
Domestic Mediumhair 2
Cat (other) 2
Terrier - Jack Russell 2
Poodle (unspecified) 2
Coton de Tuléar 1
Siamese 1
Shih Tzu 1
Shepherd Dog - German 1

Most Reported Reactions

Vomiting 15
Death by euthanasia 11
Dehydration 9
Lack of efficacy - NOS 8
Elevated blood urea nitrogen (BUN) 8
Anaemia NOS 8
Lethargy (see also Central nervous system depression in 'Neurological') 7
Anorexia 7
Neutrophilia 6
Nasal discharge 6
Not eating 6
Constipation 5

Outcome Breakdown

Outcome Unknown
20 (31.7%)
Recovered/Normal
14 (22.2%)
Ongoing
14 (22.2%)
Euthanized
11 (17.5%)
Died
4 (6.3%)

Potassium Gluconate Adverse Event Insights

66 reports name Potassium Gluconate; 15 recorded a death outcome (22.7% of reported events, not a population-level mortality rate). Active ingredient: Potassium Gluconate. Administration routes: Oral, Unknown, Topical.

By species: Cat (56 reports), Dog (8 reports), Unknown (2 reports). By breed: Domestic Shorthair (44), Unknown (3), Domestic Mediumhair (2).

Leading clinical signs: Vomiting (15), Death by euthanasia (11), Dehydration (9), Lack of efficacy - NOS (8). Outcome, 63 coded reports: Outcome Unknown leads at 31.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.