Theophylline
172 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
172
Total Reports
35
Deaths Reported
2030.0%
Death Rate
Active Ingredients
Theophylline
Administration Routes
OralUnknown
Species Affected
Dog 164
Cat 8
Most Affected Breeds
Chihuahua 22
Maltese 10
Retriever - Labrador 10
Crossbred Canine/dog 9
Beagle 8
Spitz - German Pomeranian 7
Pug 7
Shepherd Dog - Australian 7
Terrier - Yorkshire 7
Dachshund (unspecified) 7
Most Reported Reactions
Vomiting 36
Lethargy (see also Central nervous system depression in 'Neurological') 29
Death by euthanasia 21
Cough 20
Decreased appetite 17
Other abnormal test result NOS 16
Abnormal radiograph finding 16
Diarrhoea 15
Emesis 15
Seizure NOS 14
Weight loss 13
Death 13
Outcome Breakdown
Recovered/Normal
50 (29.4%)
Ongoing
45 (26.5%)
Outcome Unknown
38 (22.4%)
Euthanized
21 (12.4%)
Died
14 (8.2%)
Recovered with Sequela
2 (1.2%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.