Cbd

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49 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
49
Total Reports
10
Deaths Reported
2040.0%
Death Rate

Active Ingredients

Cbd

Administration Routes

UnknownOralTopical

Species Affected

Dog 45
Cat 3
Other Canids 1

Most Affected Breeds

Retriever - Labrador 9
Shepherd Dog - German 4
Domestic Shorthair 2
Sheepdog - Shetland 2
Retriever - Golden 2
Dog (unknown) 2
Newfoundland 2
Chihuahua 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Maltese 1

Most Reported Reactions

Lack of efficacy - NOS 9
Seizure NOS 7
Death by euthanasia 7
Drug dose administration interval too short 6
Lack of efficacy (ectoparasite) - flea 6
Ataxia 5
Urinary incontinence 5
Diarrhoea 3
Vomiting 3
Anaemia NOS 3
Intentional misuse 3
Inappropriate defecation 2

Outcome Breakdown

Ongoing
22 (44.9%)
Outcome Unknown
12 (24.5%)
Euthanized
7 (14.3%)
Recovered/Normal
5 (10.2%)
Died
3 (6.1%)

Data Summary

Metric Value
Total adverse event reports 49
Reports involving death 10
Case-fatality rate (reported events) 2040.0%
Distinct species in reports 3
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Cbd Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 49 adverse event reports referencing Cbd, including 10 reports in which the animal died — a 2040.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Cbd. Reported administration routes include Unknown, Oral, Topical. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Cbd reports are Dog (45 reports), Cat (3 reports), Other Canids (1 reports), with Dog accounting for the largest share. Within those species, Retriever - Labrador (9), Shepherd Dog - German (4), Domestic Shorthair (2) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Cbd are Lack of efficacy - NOS (9), Seizure NOS (7), Death by euthanasia (7), Drug dose administration interval too short (6). Of the 49 reports with a coded outcome, Ongoing is the leading category at 44.9%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Cbd.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial