Drug profile

The FDA adverse-event record for Cbd

51 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Cbd. Species, reactions, and outcomes follow.

#1101 of 2,679
by report volume (all drugs)
51
adverse-event reports
19.6%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Cbd ranks #1098 of 2679 by total reports (51) and #250 of 1130 by death-coded share (19.6%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1098
This drug, reports of 2679
#250
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cbd has 51 reports now versus 51 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cbd changes

Signature read: Cbd's 19.6% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
51
Total Reports
10
Deaths Reported
19.6%
Death-coded share of reports

Active Ingredients

Cbd

Administration Routes

UnknownOralTopical

Species Affected

Dog 47
Cat 3
Other Canids 1

Most Affected Breeds

Retriever - Labrador 9
Shepherd Dog - German 4
Domestic Shorthair 2
Sheepdog - Shetland 2
Retriever - Golden 2
Newfoundland 2
Dog (unknown) 2
Chihuahua 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Maltese 1

Most Reported Reactions

Lack of efficacy - NOS 9
Seizure NOS 7
Death by euthanasia 7
Drug dose administration interval too short 6
Lack of efficacy (ectoparasite) - flea 6
Ataxia 5
Urinary incontinence 5
Diarrhoea 4
Vomiting 4
Anaemia NOS 3
Intentional misuse 3
Inappropriate defecation 2

Outcome Breakdown

Ongoing
23 (45.1%)
Outcome Unknown
13 (25.5%)
Euthanized
7 (13.7%)
Recovered/Normal
5 (9.8%)
Died
3 (5.9%)

Cbd: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Cbd, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (19.6% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cbd (#1101 of 2,679 by report volume); death-coded 19.6%. PlainBreed drug row · death-coded share stamp 19.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →