Drug profile

The FDA adverse-event record for Potassium Citrate

69 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Potassium Citrate. See the species affected, top reactions, and outcomes below.

69
adverse-event reports
11.6%
death-coded share
Dog
most-reported species
15
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
69
Total Reports
8
Deaths Reported
11.6%
Death Rate

Active Ingredients

Potassium Citrate

Administration Routes

OralUnknown

Species Affected

Dog 64
Cat 5

Most Affected Breeds

Shih Tzu 10
Terrier - Yorkshire 8
Schnauzer - Miniature 5
Crossbred Canine/dog 4
Chihuahua 4
Schnauzer (unspecified) 3
Dachshund (unspecified) 3
Lhasa Apso 2
Terrier - Jack Russell 2
Maltese 2

Most Reported Reactions

Vomiting 15
Emesis 9
Lethargy (see also Central nervous system depression in 'Neurological') 8
Weight loss 8
Death by euthanasia 7
Elevated alanine aminotransferase (ALT) 7
Other abnormal test result NOS 5
Elevated serum alkaline phosphatase (SAP) 5
Elevated gamma-glutamyl transferase (GGT) 5
Diarrhoea 5
Urinary tract infection 5
Anorexia 4

Outcome Breakdown

Recovered/Normal
21 (30.4%)
Outcome Unknown
21 (30.4%)
Ongoing
16 (23.2%)
Euthanized
7 (10.1%)
Recovered with Sequela
3 (4.3%)
Died
1 (1.4%)

Potassium Citrate Adverse Event Insights

69 reports name Potassium Citrate; 8 recorded a death outcome (11.6% of reported events, not a population-level mortality rate). Active ingredient: Potassium Citrate. Administration routes: Oral, Unknown.

By species: Dog (64 reports), Cat (5 reports). By breed: Shih Tzu (10), Terrier - Yorkshire (8), Schnauzer - Miniature (5).

Leading clinical signs: Vomiting (15), Emesis (9), Lethargy (see also Central nervous system depression in 'Neurological') (8), Weight loss (8). Outcome, 69 coded reports: Recovered/Normal leads at 30.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.