Glucosamine, Chondroitin, Unsaponifiables
303 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
303
Total Reports
34
Deaths Reported
1120.0%
Death Rate
Active Ingredients
Glucosamine, Chondroitin, Unsaponifiables
Administration Routes
OralUnknown
Species Affected
Dog 297
Cat 6
Most Affected Breeds
Retriever - Labrador 77
Retriever - Golden 17
Shepherd Dog - German 12
Shepherd (unspecified) 8
Terrier (unspecified) 7
Shepherd Dog - Australian 6
Terrier - Yorkshire 6
Pug 6
Poodle - Standard 5
Mixed (Dog) 5
Most Reported Reactions
Vomiting 71
Lethargy (see also Central nervous system depression in 'Neurological') 54
Elevated alanine aminotransferase (ALT) 51
Elevated serum alkaline phosphatase (SAP) 44
Diarrhoea 35
Anorexia 35
Other abnormal test result NOS 35
Elevated total bilirubin 33
Elevated liver enzymes 28
Weight loss 25
Not eating 24
Decreased appetite 23
Outcome Breakdown
Ongoing
167 (54.9%)
Recovered/Normal
67 (22.0%)
Outcome Unknown
36 (11.8%)
Euthanized
21 (6.9%)
Died
13 (4.3%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.