Heartworm Preventative
69 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
69
Total Reports
5
Deaths Reported
720.0%
Death Rate
Active Ingredients
Heartworm Preventative
Administration Routes
OralUnknownSubcutaneousParenteral
Species Affected
Dog 69
Most Affected Breeds
Retriever - Labrador 11
Crossbred Canine/dog 10
Shepherd Dog - German 4
Retriever - Golden 4
Chihuahua 3
Schnauzer - Miniature 2
Terrier - Rat 2
Pit Bull 2
Great Pyrenees 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Most Reported Reactions
Vomiting 13
Lack of efficacy (endoparasite) - heartworm 13
Lethargy (see also Central nervous system depression in 'Neurological') 9
Emesis (multiple) 8
Diarrhoea 7
Weight loss 5
Elevated blood urea nitrogen (BUN) 5
Emesis 4
Elevated alanine aminotransferase (ALT) 4
Inappetence 4
Not eating 4
Ataxia 3
Outcome Breakdown
Recovered/Normal
27 (39.1%)
Ongoing
20 (29.0%)
Outcome Unknown
16 (23.2%)
Died
3 (4.3%)
Euthanized
2 (2.9%)
Recovered with Sequela
1 (1.4%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.