Milk Thistle
148 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
148
Total Reports
27
Deaths Reported
1820.0%
Death Rate
Active Ingredients
Milk Thistle
Administration Routes
OralUnknown
Species Affected
Dog 143
Cat 4
Other Birds 1
Most Affected Breeds
Retriever - Labrador 20
Shepherd Dog - German 7
Crossbred Canine/dog 7
Maltese 5
Collie - Border 5
Terrier - Bull - American Pit 5
Schnauzer (unspecified) 4
Dog (other) 4
Terrier - Scottish 4
Siberian Husky 4
Most Reported Reactions
Lethargy (see also Central nervous system depression in 'Neurological') 38
Vomiting 32
Elevated alanine aminotransferase (ALT) 26
Elevated serum alkaline phosphatase (SAP) 23
Other abnormal test result NOS 19
Anorexia 18
Diarrhoea 18
Seizure NOS 17
Death 15
Elevated liver enzymes 15
Elevated total bilirubin 15
Panting 15
Outcome Breakdown
Ongoing
47 (31.8%)
Outcome Unknown
38 (25.7%)
Recovered/Normal
33 (22.3%)
Died
16 (10.8%)
Euthanized
11 (7.4%)
Recovered with Sequela
3 (2.0%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.