Drug profile

The FDA adverse-event record for Canine Da2Ppv (Orig S-P Us) Lv

363 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Canine Da2Ppv (Orig S-P Us) Lv. See the species affected, top reactions, and outcomes below.

363
adverse-event reports
18.2%
death-coded share
Dog
most-reported species
113
Vomiting - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
363
Total Reports
66
Deaths Reported
18.2%
Death Rate

Active Ingredients

Canine Da2Ppv (Orig S-P Us) Lv

Administration Routes

SubcutaneousUnknownIntramuscularSubconjunctival

Species Affected

Dog 363

Most Affected Breeds

Crossbred Canine/dog 92
Retriever - Labrador 24
Chihuahua 20
Shih Tzu 18
Terrier - Yorkshire 16
Shepherd Dog - German 15
Retriever - Golden 13
Spitz - German Pomeranian 10
Pit Bull 9
Boxer (German Boxer) 8

Most Reported Reactions

Vomiting 113
Lethargy (see also Central nervous system depression in 'Neurological') 75
Diarrhoea 66
Emesis (multiple) 55
Death 39
Anorexia 28
Seizure NOS 25
Not eating 24
Death by euthanasia 24
Lack of efficacy (virus) - parvovirus (including feline panleukopenia) 22
Other abnormal test result NOS 20
Fever 19

Outcome Breakdown

Recovered/Normal
151 (40.6%)
Ongoing
112 (30.1%)
Died
42 (11.3%)
Outcome Unknown
35 (9.4%)
Euthanized
25 (6.7%)
Recovered with Sequela
7 (1.9%)

Canine Da2Ppv (Orig S-P Us) Lv Adverse Event Insights

363 reports name Canine Da2Ppv (Orig S-P Us) Lv; 66 recorded a death outcome (18.2% of reported events, not a population-level mortality rate). Active ingredient: Canine Da2Ppv (Orig S-P Us) Lv. Administration routes: Subcutaneous, Unknown, Intramuscular, Subconjunctival.

By species: Dog (363 reports). By breed: Crossbred Canine/dog (92), Retriever - Labrador (24), Chihuahua (20).

Leading clinical signs: Vomiting (113), Lethargy (see also Central nervous system depression in 'Neurological') (75), Diarrhoea (66), Emesis (multiple) (55). Outcome, 372 coded reports: Recovered/Normal leads at 40.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.