Drug profile

The FDA adverse-event record for Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia

231 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia. See the species affected, top reactions, and outcomes below.

231
adverse-event reports
87.4%
death-coded share
Cattle
most-reported species
139
Lack of efficacy (bacteria) - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
231
Total Reports
202
Deaths Reported
87.4%
Death Rate

Active Ingredients

Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia

Administration Routes

SubcutaneousIntramuscularUnknown

Species Affected

Cattle 226
Unknown 5

Most Affected Breeds

Cattle (other) 121
Mixed (Cattle) 69
Holstein-Friesian also known as Holstein 17
Aberdeen Angus 11
Unknown 5
Crossbred Bovine/Cattle 5
Cattle (unknown) 1
Texas Longhorn 1
Hereford cattle 1

Most Reported Reactions

Lack of efficacy (bacteria) - NOS 139
Death 116
Lack of efficacy - NOS 52
Abnormal test result 48
CULTURE/TITER DATA ABNORMAL 35
Increased mortality rate 31
Abnormal necropsy finding 31
Other abnormal test result NOS 27
NT - Abnormal necropsy finding NOS 26
Unrelated death 25
Pulmonary disorder NOS 19
NT - fibrinous (broncho) pneumonia/fibrinous pleuropneumonia 15

Outcome Breakdown

Died
199 (50.4%)
Outcome Unknown
167 (42.3%)
Recovered/Normal
12 (3.0%)
Ongoing
9 (2.3%)
Euthanized
6 (1.5%)
Recovered with Sequela
2 (0.5%)

Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia Adverse Event Insights

231 reports name Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia; 202 recorded a death outcome (87.4% of reported events, not a population-level mortality rate). Active ingredient: Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia. Administration routes: Subcutaneous, Intramuscular, Unknown.

By species: Cattle (226 reports), Unknown (5 reports). By breed: Cattle (other) (121), Mixed (Cattle) (69), Holstein-Friesian also known as Holstein (17).

Leading clinical signs: Lack of efficacy (bacteria) - NOS (139), Death (116), Lack of efficacy - NOS (52), Abnormal test result (48). Outcome, 395 coded reports: Died leads at 50.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.